公开(公告)号：US09321030B2

公开(公告)日：2016-04-26

申请号：US14370541

申请日：2012-12-18

Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY

Inventor： Svetlana Sukhishvili ,  Svetlana Pavlukhina

IPC: B01J20/10 ,  B01J20/28 ,  B01J20/32 ,  C08K9/08 ,  C08K3/34

CPC classification number: B01J20/10 ,  B01J20/28035 ,  B01J20/3236 ,  B01J20/3289 ,  C08K3/34 ,  C08K9/08

Abstract: A film for the retention and controlled release of organic or inorganic molecules consists essentially of a phyllosilicate clay and a organic polyanion. The film may be a built-up layered film of alternating layers of the clay and the polyanion. Organic or inorganic molecules are absorbed into the film from solution, and released in response to changes in the film's environment. The film may be built up using layer-by-layer (LbL) methods, or deposited on a substrate from a mixture of the clay and polyanion. Articles may be coated with the film by the same methods. The film is useful for the controlled release of antibiotics in response to infections, and also retains antibiotics such that bacteria may be killed by direct contact with the film.

Abstract translation: 用于保留和控制释放有机或无机分子的薄膜基本上由页硅酸盐粘土和有机聚阴离子组成。 该膜可以是粘土和聚阴离子的交替层的叠层分层膜。 有机或无机分子从溶液中吸收到膜中，并且响应于膜的环境变化而释放。 可以使用层（LbL）方法来构建膜，或者从粘土和聚阴离子的混合物沉积在基材上。 制品可以用相同的方法用薄膜包衣。 该膜对于响应于感染的抗生素的受控释放是有用的，并且还保留抗生素，使得可以通过与膜直接接触来杀死细菌。

公开(公告)号：US20150045207A1

公开(公告)日：2015-02-12

申请号：US14370541

申请日：2012-12-18

Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY

Inventor： Svetlana Sukhishvili ,  Svetlana Pavlukhina

IPC: B01J20/10 ,  B01J20/32 ,  B01J20/28

CPC classification number: B01J20/10 ,  B01J20/28035 ,  B01J20/3236 ,  B01J20/3289 ,  C08K3/34 ,  C08K9/08

Abstract: A film for the retention and controlled release of organic or inorganic molecules consists essentially of a phyllosilicate clay and a organic polyanion. The film may be a built-up layered film of alternating layers of the clay and the polyanion. Organic or inorganic molecules are absorbed into the film from solution, and released in response to changes in the film's environment. The film may be built up using layer-by-layer (LbL) methods, or deposited on a substrate from a mixture of the clay and polyanion. Articles may be coated with the film by the same methods. The film is useful for the controlled release of antibiotics in response to infections, and also retains antibiotics such that bacteria may be killed by direct contact with the film.

Abstract translation: 用于保留和控制释放有机或无机分子的薄膜基本上由页硅酸盐粘土和有机聚阴离子组成。 该膜可以是粘土和聚阴离子的交替层的叠层分层膜。 有机或无机分子从溶液中吸收到膜中，并且响应于膜的环境变化而释放。 可以使用层（LbL）方法来构建膜，或者从粘土和聚阴离子的混合物沉积在基材上。 制品可以用相同的方法用薄膜包衣。 该膜对于响应于感染的抗生素的受控释放是有用的，并且还保留抗生素，使得可以通过与膜直接接触来杀死细菌。