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公开(公告)号：US20230151021A1
公开(公告)日：2023-05-18
申请号：US17920663
申请日：2021-04-27
发明人： Erle S. Robertson , Yonggang Pei , Yanming Du
IPC分类号： C07D493/08 , A61P35/02
CPC分类号： C07D493/08 , A61P35/02
摘要： The present disclosure relates, in part, to certain compounds comprising brusatol derivatives, or a pharmaceutically acceptable salt, solvate, or polymorph thereof, which are useful for the treatment of hematological malignancies, including but not limited to leukemia and lymphoma. In certain embodiments, the present disclosure relates to pharmaceutical compositions of the compounds of the present disclosure.
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公开(公告)号：US20230220498A1
公开(公告)日：2023-07-13
申请号：US17928170
申请日：2021-05-26
发明人： Erle S. Robertson
IPC分类号： C12Q1/70
摘要： The present invention includes compositions and methods for the detection of all known respiratory agents including Coronaviruses, and the recently discovered Sars-CoV-2, the agent of the CoVID Pandemic. The invention further includes detection of immune signatures of patients infected with a Coronavirus as well as other infectious agents.
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公开(公告)号：US10883145B2
公开(公告)日：2021-01-05
申请号：US15301539
申请日：2015-04-10
发明人： Erle S. Robertson , James Alwine
IPC分类号： C12Q1/68 , C12Q1/6888 , G16B25/00 , G16B20/00
摘要： The present invention provides compositions and methods for the multiplex detection of biomarkers in an environmental, non-biological or biological sample. Compositions and methods are provided for simultaneously detecting and identifying multiple pathogens, including viruses, bacteria, fungi, protozoa and helminths, present in a sample.
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公开(公告)号：US20180291463A1
公开(公告)日：2018-10-11
申请号：US15941723
申请日：2018-03-30
发明人： Erle S. Robertson , James C. Alwine
IPC分类号： C12Q1/6886 , C12Q1/6874
摘要： The present invention includes compositions and methods for the detection of ovarian cancer. Compositions and methods are provided for detecting a metagenomic signature in a tissue sample from a subject that indicates the subject has ovarian cancer.
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公开(公告)号：US20210363598A1
公开(公告)日：2021-11-25
申请号：US17138047
申请日：2020-12-30
发明人： Erle S. Robertson , James Alwine
摘要： The present invention provides compositions and methods for the multiplex detection of biomarkers in an environmental, non-biological or biological sample. Compositions and methods are provided for simultaneously detecting and identifying multiple pathogens, including viruses, bacteria, fungi, protozoa and helminths, present in a sample.
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