公开(公告)号：US20250073204A1

公开(公告)日：2025-03-06

申请号：US18950382

申请日：2024-11-18

Applicant: TONIX PHARMACEUTICALS HOLDING CORP

Inventor： Seth Lederman ,  Darryl Rideout ,  Greg Sullivan

IPC: A61K31/397 ,  A61K31/135 ,  A61K45/06 ,  C07C211/32 ,  C07D205/04

Abstract: The present invention relates to cyclobenzaprine analogs and amitryptilene analogs, including deuterated forms useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.

公开(公告)号：US11517557B2

公开(公告)日：2022-12-06

申请号：US16630832

申请日：2018-07-13

Applicant: Tonix Pharmaceuticals Holding Corp.

Inventor： Seth Lederman ,  Darryl Rideout ,  Greg Sullivan

IPC: A61K31/397 ,  C07C211/32 ,  C07D205/04 ,  A61K45/06 ,  A61K31/135

Abstract: The present invention relates to cyclobenzaprine analogs and amitriptyline analogs, including deuterated forms useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.

公开(公告)号：US12156864B2

公开(公告)日：2024-12-03

申请号：US18075386

申请日：2022-12-05

Applicant: TONIX PHARMACEUTICALS HOLDING CORP

Inventor： Seth Lederman ,  Darryl Rideout ,  Greg Sullivan

IPC: A61K31/397 ,  A61K31/135 ,  A61K45/06 ,  C07C211/32 ,  C07D205/04

Abstract: The present invention relates to cyclobenzaprine analogs and amitriptyline analogs, including deuterated forms useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.

公开(公告)号：US20230149348A1

公开(公告)日：2023-05-18

申请号：US18075386

申请日：2022-12-05

Applicant: TONIX PHARMACEUTICALS HOLDING CORP

Inventor： Seth Lederman ,  Darryl Rideout ,  Greg Sullivan

IPC: A61K31/397 ,  A61K31/135 ,  A61K45/06 ,  C07C211/32 ,  C07D205/04

CPC classification number: A61K31/397 ,  A61K31/135 ,  A61K45/06 ,  C07C211/32 ,  C07D205/04

Abstract: The present invention relates to cyclobenzaprine analogs and amitriptyline analogs, including deuterated forms useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.

公开(公告)号：US20200230104A1

公开(公告)日：2020-07-23

申请号：US16630832

申请日：2018-07-13

Applicant: Tonix Pharmaceuticals Holding Corp.

Inventor： Seth Lederman ,  Darryl Rideout ,  Greg Sullivan

IPC: A61K31/397 ,  C07C211/32 ,  C07D205/04 ,  A61K45/06 ,  A61K31/135

Abstract: The present invention relates to cyclobenzaprine analogs useful for treatment or prevention of symptoms associated with post-traumatic stress disorder.