公开(公告)号：US20240167090A1

公开(公告)日：2024-05-23

申请号：US18498339

申请日：2023-10-31

Applicant: TOPPAN INC.

Inventor： Masayuki OGINO

IPC: C12Q1/6876 ,  C12N15/11

CPC classification number: C12Q1/6876 ,  C12N15/11 ,  C12N2310/315

Abstract: A flap probe for ICA is a single-stranded oligonucleotide having a sequence complementary to a target nucleic acid, and the flap probe has a cleavage resistant structure to the flap endonuclease at least any one position of a position before one nucleotide or a position after one nucleotide of a cleavage position due to a flap endonuclease has cleavage resistance.