公开(公告)号：US10996216B2

公开(公告)日：2021-05-04

申请号：US15552254

申请日：2016-02-26

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Noriaki Arai

IPC: G01N33/53 ,  B01L3/00 ,  G01N33/569 ,  G01N33/543

Abstract: The present invention relates to a method for applying a principle of Deterministic Lateral Displacement (DLD), and for separating cells depending on the particle sizes on the basis of the DLD principle after capturing targeted cells or untargeted cells on a carrier and thereby increasing particle sizes.

公开(公告)号：US20190085385A1

公开(公告)日：2019-03-21

申请号：US16194612

申请日：2018-11-19

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Yoichi Makino ,  Takumi Hirase ,  Noriaki Arai ,  Hiroyuki Noji

IPC: C12Q1/6858 ,  C12Q1/6825 ,  C12Q1/6855 ,  C12Q1/6876 ,  C12Q1/6818 ,  C12Q1/6827 ,  G01N21/64

Abstract: A method of detecting a target molecule including binding, to first target molecules, specific binding substances which are capable of recognizing different epitopes and labeled with nucleic acid fragments, respectively, detecting the specific binding substances based on fluorescence signals of different fluorescence wavelengths from the nucleic acid fragments, and detecting the first target molecules based on the fluorescence signals that correspond to the specific binding substances, respectively.