公开(公告)号：US20190118145A1

公开(公告)日：2019-04-25

申请号：US16089999

申请日：2017-03-30

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumi SHIMURA ,  Shun SHIMURA ,  Atsushi KOBAYASHI ,  Aya NISHIO ,  Satoko KANAMORI

IPC: B01D65/02 ,  C12H1/07 ,  B01D71/34 ,  B01D69/02 ,  B01D63/02

Abstract: The present invention relates to a method for filtering a microbial culture solution using a membrane module, said method comprising four stages including (a) cross-flow filtration of the microbial culture solution, (b) rinsing with water, (c) washing with a chemical solution and (d) rinsing with water, wherein: the filtrate passing through the membrane module in the cross-flow filtration has a total sugar concentration of 1,000-100,000 mg/1 inclusive and a protein concentration of 50-1,000 mg/l inclusive; the aforesaid stage (c) comprises step (c-1) for washing with a chemical solution containing a hypochlorite and a nonionic surfactant; and the aforesaid stages (a) to (d) are repeated in this order.

公开(公告)号：US20210163865A1

公开(公告)日：2021-06-03

申请号：US16627134

申请日：2018-06-29

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumi SHIMURA ,  Satoko KANAMORI ,  Ryota TAKAGI

IPC: C12M1/107 ,  C12M1/00 ,  C12P7/56 ,  C12P5/02 ,  B01D61/18

Abstract: Provided is a chemical product production method wherewith filterability and productivity with respect to a target substance can be both achieved. The present invention is provided with a mechanism for removing solid contents in a pipe connecting a fermentation tank and a filter separation module, and adds the solid contents removed by the removal mechanism to a culture liquid.