公开(公告)号：US20130230488A1

公开(公告)日：2013-09-05

申请号：US13888137

申请日：2013-05-06

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumiyoshi OKANO ,  Masaki SHIMIZU ,  Takanori SAITO

IPC: A61K39/00 ,  C12N5/078 ,  C12N5/0783

CPC classification number: A61K39/0011 ,  A61K38/00 ,  A61K38/19 ,  A61K2039/53 ,  C07K14/47 ,  C07K14/4748 ,  C12N5/0634 ,  C12N5/0636 ,  A61K2300/00

Abstract: The invention relates to an immunity-inducing agent comprising, as an active ingredient, at least one polypeptide having immunity-inducing activity that is selected from among polypeptides (a), (b), and (c): (a) a polypeptide of at least seven contiguous amino acids of the amino acid sequence shown by any even SEQ ID number selected from SEQ ID NOs: 2 to 30 listed in the Sequence Listing; (b) a polypeptide of at least seven amino acids having 90% or more sequence identity with the polypeptide (a); and (c) a polypeptide comprising the polypeptide (a) or (b) as a partial sequence thereof, or a recombinant vector comprising a polynucleotide encoding said polypeptide and capable of expressing said polypeptide in vivo.

Abstract translation: 本发明涉及一种免疫诱导剂，其包含作为活性成分的至少一种具有免疫诱导活性的多肽，其选自多肽（a），（b）和（c）：（a）多肽 氨基酸序列的至少七个连续氨基酸由选自序列表中所列的SEQ ID NO：2至30的任何偶数SEQ ID号表示; （b）与多肽（a）具有90％或更多序列同一性的至少7个氨基酸的多肽; 以及（c）包含多肽（a）或（b）作为其部分序列的多肽，或包含编码所述多肽并能够在体内表达所述多肽的多核苷酸的重组载体。

公开(公告)号：US20200247888A1

公开(公告)日：2020-08-06

申请号：US16800852

申请日：2020-02-25

Applicant: TORAY INDUSTRIES, INC.

Inventor： Fumiyoshi OKANO ,  Takanori SAITO ,  Takayoshi IDO ,  Masaki SHIMIZU

IPC: C07K16/28 ,  C07K16/30

Abstract: An antibody or a fragment thereof having immunoreactivity to a polypeptide comprising not less than 7 continuous amino acids in the CD179b protein, which was identified as a cancer antigen protein specifically expressed on the surfaces of cancer cells, can be used as a pharmaceutical composition for therapy and/or prophylaxis of cancer.