公开(公告)号：US20110130311A1

公开(公告)日：2011-06-02

申请号：US12993005

申请日：2008-12-22

申请人： Tae Sung Jung ,  Seong Won Nho ,  Ho Bin Jang ,  In Seok Cha ,  Sung Bin Park

发明人： Tae Sung Jung ,  Seong Won Nho ,  Ho Bin Jang ,  In Seok Cha ,  Sung Bin Park

IPC分类号： C40B60/12 ,  C12Q1/70

CPC分类号： G01N33/6848 ,  C12Q1/04 ,  G01N2333/005

摘要： Disclose herein is a method for diagnosing virus, comprising the steps of: (a) collecting a sample and lysing virus present in the sample; (b) treating the lysed sample with a specific protease to digest a protein in the sample into peptides; (c) measuring the masses of the peptides in the sample with a mass measurement device; and (d) comparing the masses of the peptides in the sample to the masses of peptides derived from known viral proteins digested with the same protease as used in step (b), thus identifying the protein from which the peptides of the sample were derived. Also disclosed is a system for diagnosing virus which can be used to carry out the above diagnostic method.

摘要翻译： 本文公开的是诊断病毒的方法，包括以下步骤：（a）收集样品并裂解存在于样品中的病毒; （b）用特异性蛋白酶处理裂解的样品以将样品中的蛋白质消化成肽; （c）用质量测量装置测量样品中肽的质量; 和（d）将样品中的肽的质量与由步骤（b）中使用的与相同蛋白酶消化的已知病毒蛋白质衍生的肽的质量进行比较，从而鉴定样品肽衍生自的蛋白质。 还公开了用于诊断病毒的系统，其可以用于执行上述诊断方法。