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1.发明授权公开(公告)号：US10550129B2
公开(公告)日：2020-02-04
申请号：US16381163
申请日：2019-04-11
IPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
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2.发明授权公开(公告)号：US10717748B2
公开(公告)日：2020-07-21
申请号：US16779797
申请日：2020-02-03
IPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
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3.发明授权公开(公告)号：US10273245B2
公开(公告)日：2019-04-30
申请号：US16194540
申请日：2018-11-19
IPC分类号： C07D498/08 , C07D405/10 , C07D405/14 , C07D413/14 , C07D401/14 , C07D413/10 , C07D417/14 , C07D401/10
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
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公开(公告)号：US09598398B2
公开(公告)日：2017-03-21
申请号：US14781963
申请日：2014-04-03
发明人： Tatsuki Koike , Masato Yoshikawa , Haruhi Ando , William John Farnaby , Shuhei Ikeda , Yuichi Kajita , Toshiya Nishi
IPC分类号： C07D401/14 , C07D403/14 , A61K31/497 , A61K31/4545 , A61K31/444 , C07D401/10 , C07D403/12 , C07D405/14 , C07D413/14 , C07D401/12 , C07D239/26 , C07D417/14 , C07D213/34 , C07D213/56 , C07D213/42
CPC分类号： C07D401/10 , C07D213/34 , C07D213/42 , C07D213/56 , C07D239/26 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention relates to a compound represented by the formula (I), which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. In the formula (I), each symbol is as defined in the specification.
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5.发明授权公开(公告)号：US11174272B2
公开(公告)日：2021-11-16
申请号：US16933092
申请日：2020-07-20
IPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.
The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.-
6.发明授权1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases 有权可用于治疗神经变性疾病的1-芳基羰基-4-氧 - 哌啶化合物公开(公告)号：US09586930B2
公开(公告)日：2017-03-07
申请号：US15221761
申请日：2016-07-28
IPC分类号： C07D401/10 , C07D401/14 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14 , C07D498/08
CPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
摘要翻译： 本发明提供可用作预防或治疗神经变性疾病等的药剂或其盐。 本发明涉及由下式表示的化合物，其中每个符号如说明书中所定义，或其盐。
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7.发明授权1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases 有权可用于治疗神经变性疾病的1-芳基羰基-4-氧 - 哌啶化合物公开(公告)号：US09193709B2
公开(公告)日：2015-11-24
申请号：US14349201
申请日：2012-10-03
IPC分类号： C07D413/10 , C07D417/14 , C07D498/08 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/10
CPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
摘要翻译： 本发明提供可用作预防或治疗神经变性疾病等的药剂或其盐。 本发明涉及由式（I）表示的化合物，其中每个符号如说明书中所定义，或其盐。
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8.发明授权公开(公告)号：US10144743B2
公开(公告)日：2018-12-04
申请号：US15424075
申请日：2017-02-03
IPC分类号： C07D498/08 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/10 , C07D413/10 , C07D417/14 , C07D405/10
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof.The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.
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9.发明授权1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases 有权可用于治疗神经变性疾病的1-芳基羰基-4-氧 - 哌啶化合物公开(公告)号：US09440990B2
公开(公告)日：2016-09-13
申请号：US14847703
申请日：2015-09-08
IPC分类号： C07D498/08 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/10 , C07D413/10 , C07D417/14
CPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
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10.发明申请1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 有权用于治疗神经损伤性疾病的1-亚油基-4-氧 - 哌啶化合物公开(公告)号：US20140228373A1
公开(公告)日：2014-08-14
申请号：US14349201
申请日：2012-10-03
IPC分类号： C07D417/14 , C07D413/10 , C07D401/14 , C07D405/14 , C07D401/10 , C07D413/14
CPC分类号： C07D498/08 , C07D401/10 , C07D401/14 , C07D405/10 , C07D405/14 , C07D413/10 , C07D413/14 , C07D417/14
摘要： The present invention provides a compound useful as an agent for the prophylaxis or treatment of neurodegenerative disease and the like, or a salt thereof. The present invention relates to a compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.
摘要翻译： 本发明提供可用作预防或治疗神经变性疾病等的药剂或其盐。 本发明涉及由式（I）表示的化合物，其中每个符号如说明书中所定义，或其盐。
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