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1.
公开(公告)号:US08563715B2
公开(公告)日:2013-10-22
申请号:US12935391
申请日:2009-03-31
申请人: Takeshi Nagata , Toshiaki Suzuki , Akira Yoshimura , Naoto Tadano , Toshiyuki Matsuno , Hideki Satoh , Kenichi Saitoh , Soichi Ohta
发明人: Takeshi Nagata , Toshiaki Suzuki , Akira Yoshimura , Naoto Tadano , Toshiyuki Matsuno , Hideki Satoh , Kenichi Saitoh , Soichi Ohta
IPC分类号: C07D239/26 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , A61K31/4545 , A61K31/496 , A61K31/506 , A61P25/00
CPC分类号: C07D239/50 , C07D239/46 , C07D239/48 , C07D239/49 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D409/06 , C07D417/04 , C07D495/04
摘要: [Problem] To provide a prophylactic/therapeutic agent against, for example, nerve diseases and the like such as ischemic brain disease and neurodegenerative disease, or a prophylactic/therapeutic agent against diseases against which antioxidant action is effective, as a cell protecting agent, in particular as an inhibitor of brain cell damage or brain cell death.[Means of Solving the Problem]A compound represented by Formula (1), or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof:
摘要翻译: 作为细胞保护剂,可以提供例如神经疾病等缺血性脑病和神经退行性疾病的预防/治疗剂或抗氧化剂作用有效的疾病的预防/治疗剂, 特别是作为脑细胞损伤或脑细胞死亡的抑制剂。 解决问题的方法由式(1)表示的化合物或其药学上可接受的盐,溶剂化物,水合物或前药:
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2.
公开(公告)号:US20110152519A1
公开(公告)日:2011-06-23
申请号:US12935391
申请日:2009-03-31
申请人: Takeshi Nagata , Toshiaki Suzuki , Akira Yoshimura , Naoto Tadano , Toshiyuki Matsuno , Hideki Satoh , Kenichi Saitoh , Soichi Ohta
发明人: Takeshi Nagata , Toshiaki Suzuki , Akira Yoshimura , Naoto Tadano , Toshiyuki Matsuno , Hideki Satoh , Kenichi Saitoh , Soichi Ohta
IPC分类号: C07D413/14
CPC分类号: C07D239/50 , C07D239/46 , C07D239/48 , C07D239/49 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D409/06 , C07D417/04 , C07D495/04
摘要: [Problem] To provide a prophylactic/therapeutic agent against, for example, nerve diseases and the like such as ischemic brain disease and neurodegenerative disease, or a prophylactic/therapeutic agent against diseases against which antioxidant action is effective, as a cell protecting agent, in particular as an inhibitor of brain cell damage or brain cell death.[Means of Solving the Problem] A compound represented by Formula (1), or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof:
摘要翻译: 作为细胞保护剂,可以提供例如神经疾病等缺血性脑病和神经退行性疾病的预防/治疗剂或抗氧化剂作用有效的疾病的预防/治疗剂, 特别是作为脑细胞损伤或脑细胞死亡的抑制剂。 解决问题的方法由式(1)表示的化合物或其药学上可接受的盐,溶剂化物,水合物或前药:
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