公开(公告)号：US06207652B1

公开(公告)日：2001-03-27

申请号：US09051284

申请日：1998-04-09

申请人： Takeshi Sakai ,  Hideo Kitano ,  Fu-Gong Yu ,  Shinji Nakayama ,  Kaoru Kojima ,  Hitomi Kimura ,  Yoshikuni Nakanishi ,  Kaoru Katayama ,  Takanari Tominaga ,  Kazuo Shimanaka ,  Katsushige Ikai ,  Ikunoshin Kato

发明人： Takeshi Sakai ,  Hideo Kitano ,  Fu-Gong Yu ,  Shinji Nakayama ,  Kaoru Kojima ,  Hitomi Kimura ,  Yoshikuni Nakanishi ,  Kaoru Katayama ,  Takanari Tominaga ,  Kazuo Shimanaka ,  Katsushige Ikai ,  Ikunoshin Kato

IPC分类号： A61K31715

CPC分类号： C12Y302/01078 ,  A61K31/737 ,  C12N9/2494 ,  C12P19/14 ,  C12Y302/01044

摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.

公开(公告)号：US06593311B2

公开(公告)日：2003-07-15

申请号：US09770504

申请日：2001-01-29

申请人： Takeshi Sakai ,  Hideo Kitano ,  Fu-Gong Yu ,  Shinji Nakayama ,  Kaoru Kojima ,  Hitomi Kimura ,  Yoshikuni Nakanishi ,  Kaoru Katayama ,  Takanari Tominaga ,  Kazuo Shimanaka ,  Katsushige Ikai ,  Ikunoshin Kato

发明人： Takeshi Sakai ,  Hideo Kitano ,  Fu-Gong Yu ,  Shinji Nakayama ,  Kaoru Kojima ,  Hitomi Kimura ,  Yoshikuni Nakanishi ,  Kaoru Katayama ,  Takanari Tominaga ,  Kazuo Shimanaka ,  Katsushige Ikai ,  Ikunoshin Kato

IPC分类号： A61K31715

CPC分类号： C12Y302/01078 ,  A61K31/737 ,  C12N9/2494 ,  C12P19/14 ,  C12Y302/01044

摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.

摘要翻译： 含有硫酸化岩藻糖的多糖和/或其降解产物的细胞凋亡诱导剂，抗癌药和抗癌药以及使用含有硫酸化岩藻糖的多糖和/或降解产物诱导细胞凋亡的方法 作为活性成分。 一种可用于生产含硫酸化岩藻糖多糖的降解产物的降解酶。