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    ARTIFICIAL LYMPH NODE FOR TREATING CANCER
    1.
    发明申请
    ARTIFICIAL LYMPH NODE FOR TREATING CANCER 失效
    人工淋巴结肿瘤治疗癌症

    公开(公告)号：US20090263428A1

    公开(公告)日：2009-10-22

    申请号：US11939885

    申请日：2007-11-14

    申请人： Takeshi WATANABE ,  Kouji TANAKA

    发明人： Takeshi WATANABE ,  Kouji TANAKA

    IPC分类号： A61K39/00 ,  C12N5/06

    CPC分类号： A61K38/195 ,  A61K35/15 ,  A61K35/26 ,  A61K35/33 ,  A61K39/0011 ,  A61K2039/5152 ,  A61K2039/5158 ,  C12N5/065 ,  C12N2533/54 ,  A61K2300/00

    摘要： Provided is an artificial lymph node that is persistently effective in cancer treatment in vivo.A method of producing an artificial lymph node capable of inducing cancer antigen-specific immune responses, comprising the following steps: (a) a step for immunizing a non-human animal using a cancer antigen and an adjuvant capable of inducing cellular immunity; and (b) a step for transplanting an artificial lymph node material consisting of a polymeric biomaterial comprising cytokine-producing stromal cells and dendritic cells to the immunized non-human animal, an artificial lymph node capable of inducing cancer antigen-specific immune responses obtained by the method of production, a cancer therapeutic agent comprising the artificial lymph node, and a kit for producing an artificial lymph node for cancer treatment comprising the following: (a) a cancer antigen; (b) an adjuvant capable of inducing cellular immunity; (c) a cytokine expression vector and stromal cells, or stromal cells incorporating a cytokine expression vector; (d) dendritic cells; and (e) a polymeric biomaterial.

    摘要翻译： 提供了一种在体内持续有效的癌症治疗的人造淋巴结。 一种产生能够诱导癌症抗原特异性免疫应答的人造淋巴结的方法，包括以下步骤：（a）使用癌抗原和能诱导细胞免疫的佐剂免疫非人动物的步骤; 和（b）将由包含产生细胞因子的基质细胞和树突状细胞的聚合生物材料构成的人造淋巴结材料移植到免疫的非人动物的步骤，能够诱导由抗原特异性免疫应答获得的癌症抗原特异性免疫应答的人造淋巴结 生产方法，包含人造淋巴结的癌症治疗剂和用于制备用于癌症治疗的人造淋巴结的试剂盒，其包括：（a）癌症抗原; （b）能诱导细胞免疫的佐剂; （c）细胞因子表达载体和基质细胞或掺入细胞因子表达载体的基质细胞; （d）树突细胞; 和（e）聚合物生物材料。

    COOLING DEVICE AND IMAGE FORMING APPARATUS INCLUDING SAME
    5.
    发明申请
    COOLING DEVICE AND IMAGE FORMING APPARATUS INCLUDING SAME 有权
    冷却装置和图像形成装置，包括它们

    公开(公告)号：US20140308058A1

    公开(公告)日：2014-10-16

    申请号：US14248652

    申请日：2014-04-09

    申请人： Keisuke IKEDA ,  Tomoyasu HIRASAWA ,  Yutaka SHOJI ,  Kenji ISHII ,  Takeshi WATANABE ,  Susumu TATEYAMA ,  Hiroaki MIYAGAWA ,  Hiromitsu FUJIYA

    发明人： Keisuke IKEDA ,  Tomoyasu HIRASAWA ,  Yutaka SHOJI ,  Kenji ISHII ,  Takeshi WATANABE ,  Susumu TATEYAMA ,  Hiroaki MIYAGAWA ,  Hiromitsu FUJIYA

    IPC分类号： G03G15/20

    CPC分类号： G03G15/6573 ,  G03G15/2017 ,  G03G15/2021 ,  G03G2215/0129

    摘要： A recording-material cooling device is disposed downstream from a fixing device in a transport direction of a recording material. The fixing device includes a fixing member and a pressing member to fix an unfixed toner image on the recording material. The recording-material cooling device includes a first cooling unit disposed at a same side as the pressing member relative to the recording material, a second cooling unit disposed at a same side as the fixing member relative to the recording material, and a third cooling unit disposed at the same side as the pressing member relative to the recording material. The first cooling unit, the second cooling unit, and the third cooling unit are arranged in an order of the first cooling unit, the second cooling unit, and the third cooling unit from upstream to downstream in the transport direction of the recording material.

    摘要翻译： 记录材料冷却装置沿着记录材料的输送方向设置在定影装置的下游。 定影装置包括固定构件和将未定影调色剂图像固定在记录材料上的按压构件。 记录材料冷却装置包括：第一冷却单元，其相对于记录材料设置在与按压构件相同的一侧;第二冷却单元，其相对于记录材料设置在与固定构件相同的一侧;第三冷却单元 相对于记录材料设置在与按压部件相同的一侧。 第一冷却单元，第二冷却单元和第三冷却单元从记录材料的输送方向的上游到下游以第一冷却单元，第二冷却单元和第三冷却单元的顺序布置。

    CONTROL UNIT FOR VEHICLE STEERING SYSTEM
    6.
    发明申请
    CONTROL UNIT FOR VEHICLE STEERING SYSTEM 有权
    车辆转向系统控制单元

    公开(公告)号：US20130066521A1

    公开(公告)日：2013-03-14

    申请号：US13602550

    申请日：2012-09-04

    申请人： Takeshi WATANABE ,  Atsushi ISHIHARA ,  Hiroshi YOSHIMOTO

    发明人： Takeshi WATANABE ,  Atsushi ISHIHARA ,  Hiroshi YOSHIMOTO

    IPC分类号： B62D6/00 ,  B62D6/02 ,  B62D5/04

    CPC分类号： B62D6/002 ,  B62D15/025

    摘要： In a control unit for a vehicle steering system, which controls an electric motor that is used to change a steering angle on the basis of a target route for a vehicle, a turning angle of a steered wheel with respect to a central axis of a shock absorber is set as a steered element angle, and the steered element angle is used in control over the electric motor.

    摘要翻译： 在用于车辆转向系统的控制单元中，其控制用于基于车辆的目标路线改变转向角的电动机，转向轮相对于冲击的中心轴线的转向角度 吸收器设置为转向元件角度，转向元件角度用于控制电动机。

    3,8-DIAMINOTETRAHYDROQUINOLINE DERIVATIVE
    7.
    发明申请
    3,8-DIAMINOTETRAHYDROQUINOLINE DERIVATIVE 有权
    3,8-二氨基四氢喹啉衍生物

    公开(公告)号：US20130012537A1

    公开(公告)日：2013-01-10

    申请号：US13617469

    申请日：2012-09-14

    申请人： Takeshi WATANABE ,  Masaru Terauchi ,  Masaaki Nagasawa ,  Kouichirou Tanaka ,  Masataka Washiduka

    发明人： Takeshi WATANABE ,  Masaru Terauchi ,  Masaaki Nagasawa ,  Kouichirou Tanaka ,  Masataka Washiduka

    IPC分类号： A61K31/4709 ,  A61P3/00 ,  A61P29/00 ,  A61P21/00 ,  A61P35/00 ,  A61P31/00

    CPC分类号： C07D401/04 ,  C07D401/06 ,  C07D401/14 ,  C07D405/06 ,  C07D409/14 ,  C07K5/06 ,  C07K5/06034 ,  C07K5/0606 ,  C07K5/06078 ,  C07K5/06156

    摘要： A method for treatment of a systemic wasting disease, by administering, to a subject in need thereof, an effective amount of a 3,8-diaminotetrahydroquinoline derivative represented by formula (Ia) (wherein X represents CH2, C═O, CH—OR, CH—SR, or CH—NRR′; m is a number of 1 or 2; Ar represents a phenyl group, a naphthyl group, a 5-membered or 6-membered aromatic heterocyclic group having one or two elements selected from S, N, and O, or a similar group; R1 and R2, which may be identical to or different from each other, each represent a hydrogen atom or a methyl group; R3 represents a C1 to C6 alkyl group or a similar group; n is a number of 0 or 1; R4 and R5, which may be identical to or different from each other, each represent a hydrogen atom, or a C1 to C6 alkyl group, etc.; and R6, R7, R, and R′, which may be identical to or different from one another, each represent a hydrogen atom or a C1 to C6 alkyl group), or a salt thereof.

    摘要翻译： 一种治疗全身性消耗性疾病的方法，通过向有需要的受试者施用有效量的由式（Ia）表示的3,8-二氨基四氢喹啉衍生物（其中X表示CH 2，C = O，CH-OR ，CH-SR或CH-NRR'; m为1或2的数; Ar表示苯基，萘基，具有一个或两个选自S的元件的5元或6元芳族杂环基， N和O或类似基团; R 1和R 2可以相同或不同，各自表示氢原子或甲基; R 3表示C 1至C 6烷基或类似基团; n为 0或1的数个;可以相同或不同的R4和R5各自表示氢原子或C1-C6烷基等; R6，R7，R和R'， 其可以彼此相同或不同，各自表示氢原子或C1-C6烷基）或其盐。

    MAGNETIC DISK DEVICE, MAGNETIC DISK, AND MAGNETIC DISK MANUFACTURING METHOD
    8.
    发明申请
    MAGNETIC DISK DEVICE, MAGNETIC DISK, AND MAGNETIC DISK MANUFACTURING METHOD 有权
    磁盘设备，磁盘和磁盘制造方法

    公开(公告)号：US20120243123A1

    公开(公告)日：2012-09-27

    申请号：US13348213

    申请日：2012-01-11

    申请人： Takeshi WATANABE

    发明人： Takeshi WATANABE

    IPC分类号： G11B5/60

    CPC分类号： G11B5/6005 ,  G11B5/72 ,  G11B5/8408

    摘要： A magnetic disk is provided wherein a non-magnetic substrate, a magnetic layer, a protection layer, and a lubrication layer are sequentially stacked. The surface of the lubrication layer has irregular structure patterns along a circumferential direction of the magnetic disk that have circumferential lengths that each correspond to a central angle. The irregular structure patterns may be formed by an adsorption between the lubrication layer and the surface of the protection layer. When a natural frequency of a magnetic head slider used to record to the magnetic disk is f and the magnetic disk rotation speed is R0, the central angle is set so as not to coincide with an angle θ0 expressed by θ0=360×(R0/60)/(f×1000).

    摘要翻译： 提供一种磁盘，其中依次层叠非磁性基板，磁性层，保护层和润滑层。 润滑层的表面沿着磁盘圆周方向具有不均匀的结构图案，其周向长度各自对应于中心角。 可以通过润滑层与保护层的表面之间的吸附形成不规则结构图案。 当用于记录到磁盘的磁头滑块的固有频率为f并且磁盘转速为R0时，中心角被设定为不与角度和角度一致; 0表示为＆thetas; 0 = 360 ×（R0 / 60）/（f×1000）。

    BIOLOGICAL OBSERVATION APPARATUS, BIOLOGICAL OBSERVATION METHOD, AND ENDOSCOPIC APPARATUS
    9.
    发明申请
    BIOLOGICAL OBSERVATION APPARATUS, BIOLOGICAL OBSERVATION METHOD, AND ENDOSCOPIC APPARATUS 审中-公开
    生物观察装置，生物观察方法和内窥镜装置

    公开(公告)号：US20100168584A1

    公开(公告)日：2010-07-01

    申请号：US12722964

    申请日：2010-03-12

    申请人： Ken FUJINUMA ,  Takeshi WATANABE

    发明人： Ken FUJINUMA ,  Takeshi WATANABE

    IPC分类号： A61B6/00

    CPC分类号： G02B23/2461 ,  A61B1/00009 ,  A61B1/0638 ,  A61B1/0646

    摘要： A biological observation apparatus comprises: a light source unit capable of selectively emitting illumination light beams of at least two or more kinds of wavelength regions; an irradiation optical system for irradiating a subject with the illumination light beams; a detection optical system for detecting scattered light beams from the subject, and acquiring respective images with respect to the respective wavelength regions; and an image processing section for performing comparison operation processing on at least two or more kinds of acquired images, wherein said two or more kinds of wavelength regions are selected so that a ratio of at least one spectral characteristic coefficient between at least one biological tissue serving as an identification target and at least another one biological tissue differing from the identification target with respect to at least one wavelength region among said wavelength regions is different from a ratio of this spectral characteristic coefficient therebetween with respect to at least another one wavelength region differing from the concerned one wavelength region among said wavelength regions.

    摘要翻译： 一种生物观察装置，包括：能够选择性地发射至少两种以上波长区域的照明光束的光源单元; 照射光学系统，用于用所述照明光束照射对象; 用于检测来自被摄体的散射光束的检测光学系统，并且获取关于各个波长区域的各个图像; 以及图像处理部分，用于对至少两种或更多种获取的图像进行比较运算处理，其中选择所述两种或更多种类型的波长区域，使得至少一种生物组织服用之间的至少一个光谱特征系数的比率 作为识别目标，并且与所述识别目标相对于所述波长区域中的至少一个波长区域不同的至少另一个生物组织与所述波长区域中的至少一个波长区域之间的所述光谱特征系数的比率不同， 所述波长区域中的相关一个波长区域。

    METHOD OF MANUFACTURING ELECTRICALLY CONDUCTIVE FILM LAMINATE AND ELECTRICALLY CONDUCTIVE FILM LAMINATE
    10.
    发明公开
    METHOD OF MANUFACTURING ELECTRICALLY CONDUCTIVE FILM LAMINATE AND ELECTRICALLY CONDUCTIVE FILM LAMINATE 审中-公开

    公开(公告)号：US20230268100A1

    公开(公告)日：2023-08-24

    申请号：US18113814

    申请日：2023-02-24

    申请人： Shinji KOH ,  Takeshi WATANABE ,  Sho KUROMATSU ,  NIHON PLAST CO., LTD.

    发明人： Kazuyuki ENDO ,  Shinji KOH ,  Takeshi WATANABE ,  Sho KUROMATSU

    IPC分类号： H01B13/00 ,  H01B13/34 ,  H01B1/04

    CPC分类号： H01B13/0036 ,  H01B13/0016 ,  H01B13/34 ,  H01B1/04

    摘要： Provided is a method of manufacturing an electrically conductive film laminate 1 including a substrate to be laminated 10, an adhesive layer 20 formed on a surface of the substrate to be laminated 10, and an electrically conductive carbon film 30 formed on a surface of the adhesive layer 20, the method including: a first laminate manufacturing step for manufacturing a first laminate 110 including a forming substrate 40 for forming the electrically conductive carbon film 30 on a surface thereof, the electrically conductive carbon film 30 formed on a surface of the forming substrate 40, and the adhesive layer 20 formed on a surface of the electrically conductive carbon film 30; a thermocompression bonding step for manufacturing a second laminate 120 by bringing the adhesive layer 20 of the first laminate 110 into contact with the substrate to be laminated 10, and then performing heating and pressure bonding; and an etching step for manufacturing the electrically conductive film laminate 1 by etching the forming substrate 40 of the second laminate 120.