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公开(公告)号:US20130005995A1
公开(公告)日:2013-01-03
申请号:US13538189
申请日:2012-06-29
申请人: Tatsuya MATSUKAWA , Noriyuki YAMAMOTO , Ryuji UENO , Hiroyuki KOTAJIMA , Shunsuke FUKUYA , Michiharu HANDA , Katsuya SAKATA
发明人: Tatsuya MATSUKAWA , Noriyuki YAMAMOTO , Ryuji UENO , Hiroyuki KOTAJIMA , Shunsuke FUKUYA , Michiharu HANDA , Katsuya SAKATA
IPC分类号: C07D309/12
CPC分类号: C07D307/30 , Y02P20/55
摘要: A method for manufacturing a fatty acid derivative represented by formula (I) is provided: wherein Z1 is wherein R3 is a protecting group for a hydroxy group; which includes the step of reacting a compound of formula (II): wherein Z2 is the same as Z1 except for when Z1 is Z2 is with a co-oxidizer under the presence of an azaadamantane-N-oxyl derivative.
摘要翻译: 提供一种制备式(I)表示的脂肪酸衍生物的方法:其中Z 1是其中R 3是羟基的保护基; 其包括使式(II)化合物:其中Z2与Z 1相同,除了当Z 1为Z 2时,其为与氧化剂在氮杂金刚烷-N-氧基衍生物存在下反应的步骤。