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公开(公告)号：US10454931B2
公开(公告)日：2019-10-22
申请号：US15001354
申请日：2016-01-20
申请人： Ted Hinaman , Steven J Rajcan , Matthew Mohr , William Gunn , Sarah K Inforzato , Robert A Johnson , Gregory J Small , David S Dodgson
发明人： Ted Hinaman , Steven J Rajcan , Matthew Mohr , William Gunn , Sarah K Inforzato , Robert A Johnson , Gregory J Small , David S Dodgson
摘要： Methods and systems for securing communications with an enterprise from a remote computing system are disclosed. One method includes initiating a secured connection with a VPN appliance associated with an enterprise using service credentials maintained in a secure applet installed on a remote computing device, and initiating communication with an authentication server within an enterprise via the secured connection. The method also includes receiving specific credentials from the authentication server, terminating the secured connection with the VPN appliance, and initiating a second secured connection with the VPN appliance using the specific credentials, the specific credentials providing access to one or more computing devices within the enterprise being within a same community of interest as the remote computing device and obfuscating one or more other computing systems within the enterprise excluded from the community of interest. The method also includes initiating communications with at least one of the one or more computing devices included in the community of interest.
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公开(公告)号：US20170208038A1
公开(公告)日：2017-07-20
申请号：US15001354
申请日：2016-01-20
申请人： Ted Hinaman , Steven J. Rajcan , Matthew Mohr , William Gunn , Sarah K. Inforzato , Robert A. Johnson , Gregory J. Small , David S. Dodgson
发明人： Ted Hinaman , Steven J. Rajcan , Matthew Mohr , William Gunn , Sarah K. Inforzato , Robert A. Johnson , Gregory J. Small , David S. Dodgson
摘要： Methods and systems for securing communications with an enterprise from a remote computing system are disclosed. One method includes initiating a secured connection with a VPN appliance associated with an enterprise using service credentials maintained in a secure applet installed on a remote computing device, and initiating communication with an authentication server within an enterprise via the secured connection. The method also includes receiving specific credentials from the authentication server, terminating the secured connection with the VPN appliance, and initiating a second secured connection with the VPN appliance using the specific credentials, the specific credentials providing access to one or more computing devices within the enterprise being within a same community of interest as the remote computing device and obfuscating one or more other computing systems within the enterprise excluded from the community of interest. The method also includes initiating communications with at least one of the one or more computing devices included in the community of interest.
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公开(公告)号：US20080085281A1
公开(公告)日：2008-04-10
申请号：US11828145
申请日：2007-07-25
申请人： Darwin Prockop , Carl Gregory , William Gunn
发明人： Darwin Prockop , Carl Gregory , William Gunn
IPC分类号： A61K39/395 , A61K38/00 , A61P17/02
CPC分类号： A61K38/17 , A61K2039/505 , C07K16/18 , C07K2317/73 , C07K2317/77 , C12N5/0663 , C12N2500/90 , C12N2501/11 , C12N2501/115 , C12N2501/415
摘要： The present invention encompasses methods and compositions for enhancing the growth of adult marrow stromal cells. The present invention also encompasses methods and compositions for regulating the effects of Dkk-1. Methods and compositions for treatment of osteolytic lesions in multiple myeloma and enhancing osteogenesis are also included.
摘要翻译： 本发明包括用于增强成人骨髓基质细胞生长的方法和组合物。 本发明还包括用于调节Dkk-1的作用的方法和组合物。 还包括治疗多发性骨髓瘤溶骨性病变和增强成骨的方法和组合物。
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公开(公告)号：US20050084494A1
公开(公告)日：2005-04-21
申请号：US10839515
申请日：2004-05-05
申请人： Darwin Prockop , Carl Gregory , William Gunn
发明人： Darwin Prockop , Carl Gregory , William Gunn
IPC分类号： C12N5/02 , C12N5/0775 , A61K39/395 , A61K33/14 , A61K38/17
CPC分类号： A61K38/17 , A61K2039/505 , C07K16/18 , C07K2317/73 , C07K2317/77 , C12N5/0663 , C12N2500/90 , C12N2501/11 , C12N2501/115 , C12N2501/415
摘要： The present invention encompasses methods and compositions for enhancing the growth of adult marrow stromal cells. The present invention also encompasses methods and compositions for regulating the effects of Dkk-1. Methods and compositions for treatment of osteolytic lesions in multiple myeloma and enhancing osteogenesis are also included.
摘要翻译： 本发明包括用于增强成人骨髓基质细胞生长的方法和组合物。 本发明还包括用于调节Dkk-1的作用的方法和组合物。 还包括治疗多发性骨髓瘤溶骨性病变和增强成骨的方法和组合物。
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