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    Propynylaminoindan Transdermal Compositions
    3.
    发明申请
    Propynylaminoindan Transdermal Compositions 有权
    丙炔基氨基茚丹透皮组合物

    公开(公告)号：US20160051489A1

    公开(公告)日：2016-02-25

    申请号：US14933598

    申请日：2015-11-05

    申请人： Teikoku Pharma USA, Inc.

    发明人： Richard D. Hamlin ,  Amit Jain ,  Jianye Wen

    IPC分类号： A61K9/70 ,  A61K31/135

    CPC分类号： A61K9/7061 ,  A61K9/7084 ,  A61K31/135

    摘要： Propynylaminoindan (e.g., Rasagiline) transdermal compositions are provided. Aspects of the transdermal compositions include a matrix which includes the propynylaminoindan, a pressure sensitive adhesive that includes an acrylate copolymer and a cationic acrylic copolymer. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions.

    摘要翻译： 提供丙炔基氨基茚满（如雷沙吉兰）透皮组合物。 透皮组合物的方面包括包含丙炔基氨基茚满的基质，包含丙烯酸酯共聚物和阳离子丙烯酸共聚物的压敏粘合剂。 还提供了使用含有透皮组合物的透皮组合物和试剂盒的方法。

    Methods and Compositions for Treating Withdrawal Syndromes Using Non-Sedative Dexmedetomidine Transdermal Compositions
    4.
    发明申请
    Methods and Compositions for Treating Withdrawal Syndromes Using Non-Sedative Dexmedetomidine Transdermal Compositions 审中-公开
    使用非镇静性美替米丹透皮组合物治疗戒断综合征的方法和组合

    公开(公告)号：US20150098983A1

    公开(公告)日：2015-04-09

    申请号：US14505943

    申请日：2014-10-03

    申请人： Teikoku Pharma USA, Inc.

    发明人： Adchara Pongpeerapat ,  Amit Jain ,  Bret Berner ,  Jianye Wen ,  Jutaro Shudo

    IPC分类号： A61K31/4174 ,  A61K9/70

    CPC分类号： A61K31/4174 ,  A61K9/7053 ,  A61K9/7061 ,  A61K47/12 ,  A61K47/32

    摘要： Aspects of the invention include methods of treating withdrawal syndrome by applying a transdermal delivery device containing a dexmedetomidine composition formulated to deliver a non-sedative amount of dexmedetomidine to a subject diagnosed as having withdrawal syndrome. In practicing methods according to certain embodiments, a transdermal delivery device having a dexmedetomidine composition is applied to a subject and is maintained in contact with the subject in a manner sufficient to deliver a non-sedative amount of dexmedetomidine to treat withdrawal syndrome in the subject. Also provided are transdermal delivery devices configured to deliver a non-sedative amount of dexmedetomidine sufficient for practicing the subject methods, as well as kits containing the transdermal delivery devices.

    摘要翻译： 本发明的方面包括通过应用含有右美托咪定组合物的透皮递送装置来治疗戒断综合征的方法，以将非镇静剂量的右美托咪定输送到被诊断为具有戒断综合征的受试者。 在根据某些实施方案的实践方法中，将具有右美托咪定组合物的透皮递送装置施用于受试者，并以足以递送非镇静剂量的右美托咪定以治疗受试者的戒断综合征的方式与受试者保持接触。 还提供了经皮递送装置，其经配置以递送非镇静剂量的足以实施本发明方法的右美托咪定，以及含有透皮递送装置的试剂盒。

    EXTENDED BUPRENORPHINE TRANSDERMAL DELIVERY COMPOSITIONS AND METHODS FOR USING THE SAME
    5.
    发明申请
    EXTENDED BUPRENORPHINE TRANSDERMAL DELIVERY COMPOSITIONS AND METHODS FOR USING THE SAME 审中-公开
    延伸的布可龙INE AL AL ERY ERY ERY ERY ERY ERY ERY AME AME AME AME AME AME AME AME AME

    公开(公告)号：US20140186421A1

    公开(公告)日：2014-07-03

    申请号：US14107643

    申请日：2013-12-16

    申请人： TEIKOKU PHARMA USA, INC.

    发明人： Amit Jain ,  Jianye Wen

    IPC分类号： A61K9/70 ,  A61K31/485

    CPC分类号： A61K9/7061 ,  A61K9/7053 ,  A61K31/485 ,  A61K47/12

    摘要： Aspects of the invention include extended transdermal delivery devices for delivering buprenorphine to a subject for an extended period of time, where the transdermal delivery devices include buprenorphine, an α-hydroxy acid and a pressure sensitive adhesive. In certain instances, buprenorphine, α-hydroxy acid and the pressure sensitive adhesive are provided as a single matrix layer formulation. Also provided are methods of using the subject extended transdermal delivery devices, as well as kits containing the extended transdermal delivery device.

    摘要翻译： 本发明的方面包括延长的透皮递送装置，其用于在长时间内向对象递送丁丙诺啡，其中透皮递送装置包括丁丙诺啡，α-羟基酸和压敏粘合剂。 在某些情况下，提供丁丙诺啡，α-羟基酸和压敏粘合剂作为单一基质层制剂。 还提供了使用受试者延长的透皮递送装置的方法，以及含有延长的透皮递送装置的试剂盒。

    Propynylaminoindan transdermal compositions
    7.
    发明授权
    Propynylaminoindan transdermal compositions 有权

    公开(公告)号：US10918607B2

    公开(公告)日：2021-02-16

    申请号：US14114679

    申请日：2013-10-25

    申请人： TEIKOKU PHARMA USA, INC.

    发明人： Richard D. Hamlin ,  Amit Jain ,  Jianye Wen

    IPC分类号： A61K9/70 ,  A61K31/135

    摘要： Propynylaminoindan (e.g., Rasagiline) transdermal compositions are provided. Aspects of the transdermal compositions include a matrix which includes the propynylaminoindan, a pressure sensitive adhesive that includes an acrylate copolymer and a cationic acrylic copolymer. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions.

    Methods and Compositions for Transdermal Delivery of a Non-Sedative Amount of Dexmedetomidine
    10.
    发明申请
    Methods and Compositions for Transdermal Delivery of a Non-Sedative Amount of Dexmedetomidine 审中-公开
    用于经皮给药的非镇静剂量的右美托咪定的方法和组合物

    公开(公告)号：US20150098981A1

    公开(公告)日：2015-04-09

    申请号：US14505936

    申请日：2014-10-03

    申请人： Teikoku Pharma USA, Inc.

    发明人： Adchara Pongpeerapat ,  Amit Jain ,  Bret Berner ,  Jianye Wen ,  Jutaro Shudo

    IPC分类号： A61K31/4174 ,  A61K9/70

    CPC分类号： A61K31/4174 ,  A61K9/7053 ,  A61K9/7061 ,  A61K47/12 ,  A61K47/14 ,  A61K47/32

    摘要： Aspects of the invention include methods for applying to a subject a transdermal delivery device configured to deliver a non-sedative amount of a dexmedetomidine composition. In practicing methods according to certain embodiments, a non-sedative amount of a dexmedetomidine composition is transdermally applied to a subject and is maintained in contact with the subject in a manner sufficient to deliver a non-sedative amount of dexmedetomidine to a subject. Also provided are transdermal delivery devices having a non-sedative amount of dexmedetomidine sufficient for practicing the subject methods, as well as kits containing the transdermal delivery devices.

    摘要翻译： 本发明的方面包括向受试者施用经配置以递送非镇静剂量右美托咪定组合物的透皮递送装置的方法。 在根据某些实施方案的实践方法中，非镇静剂量的右美托咪定组合物经皮施用于受试者，并且以足以将非镇静剂量的右美托咪定输送给受试者的方式与受试者保持接触。 还提供了具有足够实践本发明方法的非镇静剂量的右美托咪定的透皮递送装置，以及含有透皮递送装置的试剂盒。