公开(公告)号：US20190298661A1

公开(公告)日：2019-10-03

申请号：US16346180

申请日：2017-10-31

Applicant: The Corporation of Mercer University

Inventor： Kevin S. Murnane ,  Ajay K. Banga ,  Sindhu S. Ganti ,  Ying Jiang ,  Ashana Puri

IPC: A61K9/70 ,  A61K31/5375 ,  A61K31/4465 ,  A61K9/00

Abstract: Transdermal patches and transdermally applyable pharmaceutical compositions containing an effective amount of at least one drug are disclosed. The at least one drug may be: (a) phenmetrazine; (b) 4-benzylpiperidine; (c) 3-flouroamphetamine; (d) a DA/NE releaser compound having formula (I): wherein each of R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 is independently hydrogen, a halogen, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted alkoxy group, and when one or more substituents is present on an alkyl group, an alkoxy group, or both, each substituent is independently a halogen; or (e) any combination thereof. Methods of making transdermal patches and transdermally applyable pharmaceutical compositions and methods of using transdermal patches and transdermally applyable pharmaceutical compositions are also disclosed.