公开(公告)号：US20240361337A1

公开(公告)日：2024-10-31

申请号：US18660434

申请日：2024-05-10

Applicant: The Curators of the University of Missouri

Inventor： James L. Cook ,  Aaron M. Stoker ,  Chantelle C. Bozynski ,  Keiichi Kuroki ,  Cristi R. Cook ,  Emily Leary

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N2800/60

Abstract: Methods for predicting canine hip dysplasia (CHD) in an immature canine subject are provided. The methods include the use of concentration profiles of a plurality of polypeptides, including C2C, CTX-I, CTX-II, RANKL, PIICP, COMP, PINP. Also provided are CHD biomarker profiles for predicting or diagnosing CHD in immature or young canines before CHD develops. Diagnostic reagents and kits for the same are also provided.

公开(公告)号：US20210239711A1

公开(公告)日：2021-08-05

申请号：US17168871

申请日：2021-02-05

Applicant: The Curators of the University of Missouri

Inventor： James L. Cook ,  Aaron M. Stoker ,  Chantelle C. Bozynski ,  Keiichi Kuroki ,  Cristi R. Cook ,  Emily Leary

IPC: G01N33/68

Abstract: Methods for predicting canine hip dysplasia (CHD) in an immature canine subject are provided. The methods include the use of concentration profiles of a plurality of polypeptides, including C2C, CTX-I, CTX-II, RANKL, PIICP, COMP, PINP. Also provided are CHD biomarker profiles for predicting or diagnosing CHD in immature or young canines before CHD develops. Diagnostic reagents and kits for the same are also provided.