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1.发明公开公开(公告)号：US20240345376A1
公开(公告)日：2024-10-17
申请号：US18642730
申请日：2024-04-22
发明人： Inhee Chung
IPC分类号： G02B21/00
CPC分类号： G02B21/0088 , G02B21/0064 , G02B21/0068 , G02B21/0072
摘要： Systems and methods for microscopic imaging include an inverted microscope directed at a sample on a coverglass, where the sample is comprised of one or more cells and one or more chromophores. A ridge separates the coverglass from a silicon dioxide layer, and a silicon mirror is situated on the silicon dioxide layer, opposite the ridge and coverglass, while a weight is situated against the silicon mirror, opposite the silicon dioxide layer. The inverted microscope uses a spatial light modulator to diffract light through a linear polarizer and a filter wheel comprised of one or more Fourier filters. A beam or beams of s-polarized light is directed to the silicon mirror to create axial light modulation with its reflection on the silicon mirror, producing image data that is captured at a light detector.
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公开(公告)号：US20220341937A1
公开(公告)日：2022-10-27
申请号：US17727628
申请日：2022-04-22
发明人： Inhee Chung
IPC分类号： G01N33/574 , A61K45/06
摘要： Embodiments of the instant disclosure relate to novel methods and compositions for distinguishing high-grade ductal carcinoma in situ (DCIS) from lower-grade DCIS in a breast tissue. Other embodiments of the instant disclosure provide for methods of administering one or more appropriate breast cancer treatment regimens to a subject diagnosed with high-risk DCIS.
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公开(公告)号：US12013398B2
公开(公告)日：2024-06-18
申请号：US17727628
申请日：2022-04-22
发明人： Inhee Chung
IPC分类号： G01N33/574 , A61K45/06
CPC分类号： G01N33/57492 , A61K45/06
摘要： Embodiments of the instant disclosure relate to novel methods and compositions for distinguishing high-grade ductal carcinoma in situ (DCIS) from lower-grade DCIS in a breast tissue. Other embodiments of the instant disclosure provide for methods of administering one or more appropriate breast cancer treatment regimens to a subject diagnosed with high-risk DCIS.
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