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    Immunosuppressive agent and food
    1.
    发明申请
    Immunosuppressive agent and food 审中-公开
    免疫抑制剂和食物

    公开(公告)号：US20040048828A1

    公开(公告)日：2004-03-11

    申请号：US10395274

    申请日：2003-03-25

    申请人： The Japan Research and Development Association for New Functional Foods

    发明人： Nobukazu Onishi ,  Kunihiko Hashimoto ,  Hisao Shimizu

    IPC分类号： A61K031/736

    CPC分类号： A61K31/736 ,  A23L33/10 ,  A23V2002/00 ,  A23V2250/5058

    摘要： An immunosuppressive agent and food, which can prevent type I allergic diseases, autoimmune diseases, rejections in organ transplant and improve morbid states even when these diseases are induced, and which are safe and easy to intake. The immunosuppressive agent and food contain a fine powder of a hydrophilic polysaccharide. Preferably, the fine powder of hydrophilic polysaccharide is in the form of glucomannan which is refined konjak flour, has a dietary fiber content of 90% or more, and is easily soluble in water. For making the glucomannan into an easily water-soluble state, it is preferably subjected to a pulverization treatment. Preferably, the glucomannan subjected to the pulverization treatment has a weight average molecular weight of 1,000,000 or more and an average particle diameter of 100 nullm or less, and a period of time until 1% aqueous solution thereof reaches the viscosity peak at room temperature is within 30 minutes. As a fort, powder, capsule, tablet, pill or granule may be mentioned.

    摘要翻译： 免疫抑制剂和食物，可以预防I型过敏性疾病，自身免疫性疾病，器官移植排斥反应，甚至在诱发这些疾病时也能改善病态，并且安全且容易摄入。 免疫抑制剂和食物含有亲水性多糖的细粉末。 优选地，亲水性多糖的细粉末是葡聚糖的形式，其是精制魔芋粉，具有90％以上的膳食纤维含量，并且易溶于水。 为了使葡甘露聚糖易于水溶性状态，优选进行粉碎处理。 优选地，进行粉碎处理的葡甘露聚糖的重均分子量为1,000,000以上，平均粒径为100μm以下，直到1％水溶液在室温下达到粘度峰值的时间在 30分钟。 作为堡垒，可以提及粉末，胶囊，片剂，丸剂或颗粒剂。