公开(公告)号：US20200337641A1

公开(公告)日：2020-10-29

申请号：US16760431

申请日：2018-11-02

Applicant: The Regents of the University of California

Inventor： Joseph Wang ,  Juliane Sempionatto Moreto ,  Jonas Felipe Kurniawan ,  Aida Martin Galan ,  Jayoung Kim ,  Alan Campbell ,  Jose Roberto Moreto

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/05

Abstract: Disclosed are devices, systems and methods for epidermal monitoring of a fluid on skin. In some aspects, a device includes an electrochemical sensor comprising two or more electrodes disposed on a first flexible substrate; a microfluidic device comprising a second flexible substrate coupled to the first substrate and structured to include (i) a channel in a first cavity of the second substrate, (ii) one or more holes that connect to the channel and provide one or more inlets, and (iii) a reservoir connected to the channel, in which the electrochemical sensor is aligned with the reservoir; and an adhesion layer coupled to the microfluidic device and attachable to skin, and the device being operable to detect a biomarker in a fluid in secreted by the skin into the microfluidic device.