公开(公告)号：US09530928B2

公开(公告)日：2016-12-27

申请号：US14103725

申请日：2013-12-11

申请人： The Regents of the University of California

发明人： Shimon Weiss ,  Marcel Bruchez ,  Paul A. Alivisatos

IPC分类号： G01N33/50 ,  H01L33/00 ,  B82Y15/00 ,  C09K11/02 ,  C09K11/56 ,  C09K11/88 ,  C09K11/89 ,  C12Q1/68 ,  G01N33/533 ,  G01N33/542 ,  G01N33/543 ,  G01N33/58 ,  G01N33/48

CPC分类号： H01L33/0062 ,  B82Y15/00 ,  C09K11/025 ,  C09K11/565 ,  C09K11/883 ,  C09K11/89 ,  C09K11/892 ,  C12Q1/6816 ,  C12Q2563/107 ,  G01N33/533 ,  G01N33/542 ,  G01N33/54373 ,  G01N33/588 ,  H01L33/0083 ,  Y10T436/141111 ,  Y10T436/142222

摘要： A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more semiconductor nanocrystal compounds are linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and capable of, in response to exposure to a first energy, providing a second energy. Also described are processes for respectively: making the semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and treating materials with the probe.

摘要翻译： 描述了半导体纳米晶体化合物和探针。 该化合物能够连接至一个或多个亲和分子。 化合物包括（1）能够响应于暴露于第一能量提供第二能量的一种或多种半导体纳米晶体，和（2）一种或多种连接剂，其具有连接到所述一种或多种半导体纳米晶体的第一部分 和能够连接到一个或多个亲和分子的第二部分。 一个或多个半导体纳米晶体化合物与一个或多个亲和分子连接以形成半导体纳米晶体探针，该半导体纳米晶体探针能够与正在分析的材料中的一种或多种可检测物质结合，并且能够响应于暴露于第一能量而提供 第二节能量。 还描述了分别制造半导体纳米晶体化合物的方法; 制造半导体纳米晶体探针; 并用探针处理材料。

公开(公告)号：US20170323998A1

公开(公告)日：2017-11-09

申请号：US15385377

申请日：2016-12-20

申请人： The Regents of the University of California

发明人： Shimon Weiss ,  Marcel Bruchez ,  Paul A. Alivisatos

IPC分类号： H01L33/00 ,  G01N33/58 ,  B82Y15/00 ,  C09K11/02 ,  G01N33/543 ,  C09K11/56 ,  G01N33/533 ,  C12Q1/68 ,  C09K11/89 ,  C09K11/88 ,  G01N33/542

CPC分类号： H01L33/0062 ,  B82Y15/00 ,  C09K11/025 ,  C09K11/565 ,  C09K11/883 ,  C09K11/89 ,  C09K11/892 ,  C12Q1/6816 ,  C12Q2563/107 ,  G01N33/533 ,  G01N33/542 ,  G01N33/54373 ,  G01N33/588 ,  H01L33/0083 ,  Y10T436/141111 ,  Y10T436/142222

摘要： A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more semiconductor nanocrystal compounds are linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and capable of, in response to exposure to a first energy, providing a second energy. Also described are processes for respectively: making the semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and treating materials with the probe.

公开(公告)号：US20140179046A1

公开(公告)日：2014-06-26

申请号：US14103725

申请日：2013-12-11

申请人： The Regents of the University of California

发明人： Shimon Weiss ,  Marcel Bruchez ,  Paul A. Alivisatos

IPC分类号： H01L33/00

CPC分类号： H01L33/0062 ,  B82Y15/00 ,  C09K11/025 ,  C09K11/565 ,  C09K11/883 ,  C09K11/89 ,  C09K11/892 ,  C12Q1/6816 ,  C12Q2563/107 ,  G01N33/533 ,  G01N33/542 ,  G01N33/54373 ,  G01N33/588 ,  H01L33/0083 ,  Y10T436/141111 ,  Y10T436/142222

摘要： A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second energy, and (2) one or more linking agents, having a first portion linked to the one or more semiconductor nanocrystals and a second portion capable of linking to one or more affinity molecules. One or more semiconductor nanocrystal compounds are linked to one or more affinity molecules to form a semiconductor nanocrystal probe capable of bonding with one or more detectable substances in a material being analyzed, and capable of, in response to exposure to a first energy, providing a second energy. Also described are processes for respectively: making the semiconductor nanocrystal compound; making the semiconductor nanocrystal probe; and treating materials with the probe.

摘要翻译： 描述了半导体纳米晶体化合物和探针。 该化合物能够连接至一个或多个亲和分子。 化合物包括（1）能够响应于暴露于第一能量提供第二能量的一种或多种半导体纳米晶体，和（2）一种或多种连接剂，其具有连接到所述一种或多种半导体纳米晶体的第一部分 和能够连接到一个或多个亲和分子的第二部分。 一个或多个半导体纳米晶体化合物与一个或多个亲和分子连接以形成半导体纳米晶体探针，该半导体纳米晶体探针能够与正在分析的材料中的一种或多种可检测物质结合，并且能够响应于暴露于第一能量而提供 第二节能量。 还描述了分别制造半导体纳米晶体化合物的方法; 制造半导体纳米晶体探针; 并用探针处理材料。