-
公开(公告)号:US20210299219A1
公开(公告)日:2021-09-30
申请号:US17235653
申请日:2021-04-20
发明人: Sunil Chauhan , Reza Dana
IPC分类号: A61K38/18 , C07K14/475 , C07K14/00 , A61P27/02 , A61K9/00
摘要: This application discloses ophthalmic formulations and methods for treating and preventing corneal haze and scarring with an hepatocyte growth factor (HGF) agent.
-
公开(公告)号:US20180256685A1
公开(公告)日:2018-09-13
申请号:US15759203
申请日:2016-09-09
发明人: Sunil Chauhan , Reza Dana
CPC分类号: A61K38/1833 , A61K9/0048 , A61P27/02 , C07K14/00 , C07K14/4753
摘要: This application discloses ophthalmic formulations and methods for treating and preventing corneal haze and scarring with an hepatocyte growth factor (HGF) agent.
-
公开(公告)号:US09872901B2
公开(公告)日:2018-01-23
申请号:US15063088
申请日:2016-03-07
发明人: Reza Dana , Sunil Chauhan
IPC分类号: A61K39/00 , A61K9/00 , A61K39/395 , A61K31/724 , A61K31/728 , A61K38/17 , A61K38/20 , A61K45/06 , C07K14/54 , C07K16/24 , C07K16/28
CPC分类号: A61K39/3955 , A61K9/0048 , A61K9/0051 , A61K31/724 , A61K31/728 , A61K38/1793 , A61K38/20 , A61K45/06 , A61K2039/505 , C07K14/54 , C07K16/244 , C07K16/2866 , C07K2317/75 , C07K2317/76 , A61K2300/00
摘要: The invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-17 and methods for using this composition to treat IL-17-mediated ocular inflammatory disorders. The invention also discloses devices for delivering this composition to the eye.
-
4.
公开(公告)号:US20160361412A1
公开(公告)日:2016-12-15
申请号:US15063088
申请日:2016-03-07
发明人: Reza Dana , Sunil Chauhan
IPC分类号: A61K39/395 , C07K16/28 , C07K16/24 , A61K9/00 , A61K45/06
CPC分类号: A61K39/3955 , A61K9/0048 , A61K9/0051 , A61K31/724 , A61K31/728 , A61K38/1793 , A61K38/20 , A61K45/06 , A61K2039/505 , C07K14/54 , C07K16/244 , C07K16/2866 , C07K2317/75 , C07K2317/76 , A61K2300/00
摘要: The invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-17 and methods for using this composition to treat IL-17-mediated ocular inflammatory disorders. The invention also discloses devices for delivering this composition to the eye.
摘要翻译: 本发明包括具有抑制炎性细胞因子IL-17功能的方法的组合物和使用该组合物治疗IL-17介导的眼部炎症性疾病的方法。 本发明还公开了用于将该组合物递送至眼睛的装置。
-
公开(公告)号:US11306140B2
公开(公告)日:2022-04-19
申请号:US16068300
申请日:2017-01-06
发明人: Reza Dana , Sunil Chauhan , Yihe Chen
摘要: Methods and compositions for reducing the activity or number of memory Th17 cells in ocular tissue, and for treatment and/or prevention of ocular immunoinflammatory diseases are described.
-
公开(公告)号:US11241497B2
公开(公告)日:2022-02-08
申请号:US15842604
申请日:2017-12-14
发明人: Reza Dana , Sunil Chauhan
IPC分类号: A61K39/395 , A61K31/724 , A61K31/728 , A61K9/00 , A61K38/17 , A61K38/20 , A61K45/06 , C07K14/54 , C07K16/24 , C07K16/28 , A61K39/00
摘要: The invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-17 and methods for using this composition to treat IL-17-mediated ocular inflammatory disorders. The invention also discloses devices for delivering this composition to the eye.
-
公开(公告)号:US10449234B2
公开(公告)日:2019-10-22
申请号:US15759203
申请日:2016-09-09
发明人: Sunil Chauhan , Reza Dana
IPC分类号: A61K38/18 , C07K14/00 , C07K14/475 , A61P27/02 , A61K9/00
摘要: This application discloses ophthalmic formulations and methods for treating and preventing corneal haze and scarring with an hepatocyte growth factor (HGF) agent.
-
公开(公告)号:US20190008765A1
公开(公告)日:2019-01-10
申请号:US16068300
申请日:2017-01-06
发明人: Reza Dana , Sunil Chauhan , Yihe Chen
摘要: Methods and compositions for reducing the activity or number of memory Th17 cells in ocular tissue, and for treatment and/or prevention of ocular immunoinflammatory diseases are described.
-
公开(公告)号:US20150307619A1
公开(公告)日:2015-10-29
申请号:US14651991
申请日:2013-12-13
发明人: Reza Dana , Sunil Chauhan , Shilpa Kodati , Daniel Saban
IPC分类号: C07K16/28 , C07K14/705 , A61K47/48 , A61K45/06 , A61K31/7088 , A61K39/395
CPC分类号: C07K16/2896 , A61K31/7088 , A61K39/39533 , A61K45/06 , A61K47/6803 , A61K2039/505 , A61K2039/54 , C07K14/70596 , C07K16/2866 , C07K2317/24 , C07K2317/622 , C07K2317/73
摘要: This application discloses ophthalmic formulations and methods for treating dry eye disease with a C-C chemokine receptor type 7 (CCR7) inhibitor.
摘要翻译: 本申请公开了用C-C趋化因子受体7型(CCR7)抑制剂治疗干眼病的眼用制剂和方法。
-
公开(公告)号:US20180092976A1
公开(公告)日:2018-04-05
申请号:US15842604
申请日:2017-12-14
发明人: Reza Dana , Sunil Chauhan
IPC分类号: A61K39/395 , C07K16/28 , A61K9/00 , A61K31/724 , A61K31/728 , A61K38/17 , A61K38/20 , C07K16/24 , C07K14/54
CPC分类号: A61K39/3955 , A61K9/0048 , A61K9/0051 , A61K31/724 , A61K31/728 , A61K38/1793 , A61K38/20 , A61K45/06 , A61K2039/505 , C07K14/54 , C07K16/244 , C07K16/2866 , C07K2317/75 , C07K2317/76 , A61K2300/00
摘要: The invention comprises a composition with means to inhibit the function of the inflammatory cytokine IL-17 and methods for using this composition to treat IL-17-mediated ocular inflammatory disorders. The invention also discloses devices for delivering this composition to the eye.
-
-
-
-
-
-
-
-
-