公开(公告)号：US20240131032A1

公开(公告)日：2024-04-25

申请号：US17768616

申请日：2020-10-15

Applicant: The Scripps Research Institute

Inventor： Benjamin CRAVATT ,  Ekaterina VINOGRADOVA ,  Vincent CROWLEY ,  Xiaoyu ZHANG ,  Michael Andreas SCHAFROTH ,  Minoru YOKOYAMA ,  Dave REMILLARD ,  Bruno MELILLO ,  Stuart SCHREIBER

IPC: A61K31/5377 ,  A61K31/167 ,  A61K31/357 ,  A61K31/437 ,  A61K31/444 ,  A61K31/4468 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/47 ,  A61K31/496 ,  A61K31/506 ,  A61K31/517 ,  A61K31/55 ,  A61K39/39 ,  A61P35/00

CPC classification number: A61K31/5377 ,  A61K31/167 ,  A61K31/357 ,  A61K31/437 ,  A61K31/444 ,  A61K31/4468 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/47 ,  A61K31/496 ,  A61K31/506 ,  A61K31/517 ,  A61K31/55 ,  A61K39/39 ,  A61P35/00 ,  A61K2039/55511

Abstract: Disclosed herein are methods, pharmaceutical compositions, and vaccines for modulating an immune response. Also disclosed herein are methods, pharmaceutical compositions, and vaccines for inducing an immune response.

公开(公告)号：US20250034216A1

公开(公告)日：2025-01-30

申请号：US18712449

申请日：2022-11-21

Applicant: The Scripps Research Institute

Inventor： Benjamin CRAVATT ,  Jarrett REMSBERG ,  Michael LAZEAR ,  Minoru YOKOYAMA ,  Michael SCHAFROTH ,  Daisuke OGASAWARA ,  Kristen DEMEESTER ,  Evert NJOMEN ,  Bruno MELILLO ,  Stuart SCHREIBER

IPC: C07K14/47

Abstract: Provided are in vivo engineered proteins. The engineered protein may be covalently bound to a ligand.