公开(公告)号：US20240041704A1

公开(公告)日：2024-02-08

申请号：US18342056

申请日：2023-06-27

申请人： The University of Hong Kong

发明人： Ollie YiRu YU ,  Ying Kei LUNG ,  Chun Hung CHU ,  Xing Yun GE

IPC分类号： A61K6/889 ,  A61K6/853 ,  A61K6/887 ,  A61K6/844

CPC分类号： A61K6/889 ,  A61K6/853 ,  A61K6/887 ,  A61K6/844

摘要： The subject invention pertains to a novel glass-ionomer cement (NGIC) that provides an alternative restorative material for dental amalgams being phased out; has improved mechanical properties compared to conventional glass-ionomer cement (GIC) products; has improved adhesive properties compared to conventional GIC products; provides sufficient biocompatibility; can release ions to promote remineralization of the teeth, which inhibits tooth decay; can inhibit growth of bacteria, which inhibits tooth decay; provides increased retention time and decreased frequency of replacement in the oral cavity. Formulations of the subject invention can include powders and solutions containing silicate glass, poly(vinylphosphonic acid) (PVPA), nanosilver bioactive glass, and polyacrylic acid.