公开(公告)号：US10921257B2

公开(公告)日：2021-02-16

申请号：US15793120

申请日：2017-10-25

Applicant: The University of Massachusetts

Inventor： Lili He

IPC: G01N21/65 ,  G01N33/50 ,  G01J3/44 ,  B82Y15/00

Abstract: The present disclosure provides a method for mapping one or more analytes that contact a biological structure. The method uses surface-enhanced Raman spectroscopy and includes contacting the biological structure and a metallic nanoparticle. The method further includes collecting a spectrum with a Raman spectrometer. The method further includes determining a location of the analyte along at least one of an x-direction, a y-direction and a z-direction on the structure.

公开(公告)号：US20180113075A1

公开(公告)日：2018-04-26

申请号：US15793120

申请日：2017-10-25

Applicant: The University of Massachusetts

Inventor： Lili He

IPC: G01N21/65 ,  G01J3/44 ,  G01N33/50

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/44 ,  G01N33/50

Abstract: The present disclosure provides a method for mapping one or more analytes that contact a biological structure. The method uses surface-enhanced Raman spectroscopy and includes contacting the biological structure and a metallic nanoparticle. The method further includes collecting a spectrum with a Raman spectrometer. The method further includes determining a location of the analyte along at least one of an x-direction, a y-direction and a z-direction on the structure.