公开(公告)号：US20240287106A1

公开(公告)日：2024-08-29

申请号：US18568401

申请日：2022-06-09

Applicant: The University of Tokyo ,  RIKEN

Inventor： Toru Komatsu ,  Yasuteru Urano ,  Shingo Sakamoto ,  Rikiya Watanabe ,  Yu Kagami

IPC: C07F9/38 ,  C12Q1/37

CPC classification number: C07F9/38 ,  C12Q1/37

Abstract: To provide a synthesis scheme capable of easily synthesizing various kinds of fluorescent probes. A method for preparing a compound represented by Formula (III) below, the method including steps (1) to (5).

公开(公告)号：US10815379B2

公开(公告)日：2020-10-27

申请号：US15561444

申请日：2016-01-15

Applicant: The University of Tokyo

Inventor： Kenjiro Hanaoka ,  Yu Kagami ,  Tetsuo Nagano ,  Yasuteru Urano

IPC: C09B11/26 ,  G01N33/52 ,  C12Q1/04 ,  C07F7/12 ,  C09K11/06 ,  G01N21/80 ,  G01N33/48 ,  C07F7/10 ,  C07F7/08 ,  C09B11/28 ,  G01N21/77

Abstract: Fluorescent probes and their salts have high fluorescence quantum yield and high resistance to photobleaching suitable for visualizing various pH environments within cells such as weakly basic, neutral, and weakly acidic environments. The fluorescent probes can have the following structure: