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    Modified minigastrin analogs for oncology applications
    1.
    发明申请
    Modified minigastrin analogs for oncology applications 审中-公开
    用于肿瘤学应用的改良的minigastrin类似物

    公开(公告)号：US20070041903A1

    公开(公告)日：2007-02-22

    申请号：US11206757

    申请日：2005-08-19

    申请人： Theodosia Maina ,  Berthold Noll ,  Thomas Behr ,  Martin BEHE

    发明人： Theodosia Maina ,  Berthold Noll ,  Thomas Behr ,  Martin BEHE

    IPC分类号： A61K51/00 ,  C07K7/08

    CPC分类号： A61K51/088 ,  C07K14/595

    摘要： The invention is directed to modified minigastrin analogs. It further relates to labeling such modified minigastrin analogs with metallic radionuclides. The invention further relates to methods for making such novel modified minigastrin analogs, their labeling with metallic radionuclides and their use in oncology applications as in the targeted diagnostic imaging and staging of CCK-2/gastrin-R-positive neoplasms in man with SPECT (technetium-99m), or PET (technetium-94m), or eventually in targeted radionuclide therapy (rhenium-188).

    摘要翻译： 本发明涉及修饰的minigastrin类似物。 它还涉及用金属放射性核素标记这种经修饰的minigastrin类似物。 本发明还涉及制备这种新型修饰的微型中性粒细胞类似物的方法，它们用金属放射性核素的标记及其在肿瘤学应用中的应用，如在用SPECT（锝）的人中CCK-2 /胃泌素-R阳性赘生物的靶向诊断成像和分期 -99m）或PET（锝-94m），或最终在靶向放射性核素治疗（铼-188）中。

    Method for controlling the combustion in a combustion chamber and combustion chamber device
    2.
    发明申请
    Method for controlling the combustion in a combustion chamber and combustion chamber device 审中-公开
    用于控制燃烧室和燃烧室装置中的燃烧的方法

    公开(公告)号：US20090205309A1

    公开(公告)日：2009-08-20

    申请号：US12380288

    申请日：2009-02-24

    申请人： Berthold Noll

    发明人： Berthold Noll

    IPC分类号： F02C7/057 ,  F02C3/32

    CPC分类号： F23C7/02 ,  F23C2900/09002 ,  F23R3/16 ,  F23R3/26

    摘要： There is provided a method for controlling the combustion in a combustion chamber with a combustion space, wherein fuel in fluid form and oxidiser in fluid form are blown into the combustion space, in which at least one control jet is generated in the combustion space, which influences the flow of fuel and/or oxidiser in the combustion space, wherein the mass flow component of the at least one control jet lies between 1% and 7% of the total mass flow, the at least one control jet is generated such that it varies over time, the at least one control jet is generated by being blown in or extracted through one or more ports in a combustion chamber wall, which coincide with one or more ports for blowing in and/or extracting fuel and/or oxidiser, and the at least one control jet is generated so that a degree of swirl of the fuel flow and/or oxidiser flow is reduced by means thereof.

    摘要翻译： 提供了一种用于控制具有燃烧空间的燃烧室中的燃烧的方法，其中流体形式的燃料和流体形式的氧化剂被吹入燃烧空间中，其中在燃烧空间中产生至少一个控制射流， 影响燃烧空间中的燃料和/或氧化剂的流动，其中至少一个控制射流的质量流量成分在总质量流量的1％至7％之间，产生至少一个控制射流， 随时间变化，通过在燃烧室壁中的一个或多个端口吹入或抽出至少一个控制喷射器，其与用于吹入和/或提取燃料和/或氧化剂的一个或多个端口重合，以及 产生至少一个控制射流，使得燃料流和/或氧化剂流的旋转程度通过其减少。