Turbine Blade With Recessed Tip
    1.
    发明申请
    Turbine Blade With Recessed Tip 审中-公开
    涡轮叶片带有凹入尖端

    公开(公告)号:US20090180887A1

    公开(公告)日:2009-07-16

    申请号:US12087761

    申请日:2007-01-15

    IPC分类号: F01D5/14

    摘要: A turbine blade (1) with a side surface (7) having an aerodynamic profile. The turbine blade (1) further comprises an end surface (6) and is mounted in a turbine, whereby the end surface (6) is delimited by a gap from a casing (8) of the turbine. The end surface (6) comprises a recess (2) which is shaped such that it acts as an improved aerodynamic seal.

    摘要翻译: 具有侧表面(7)具有空气动力学特性的涡轮叶片(1)。 涡轮叶片(1)还包括端面(6)并且安装在涡轮机中,由此端面(6)由与涡轮机的壳体(8)的间隙限定。 端面(6)包括凹部(2),其形状使得其用作改进的空气动力学密封。

    Lightweight Crankshaft
    5.
    发明申请
    Lightweight Crankshaft 审中-公开
    轻型曲轴

    公开(公告)号:US20070277645A1

    公开(公告)日:2007-12-06

    申请号:US10487030

    申请日:2002-08-13

    IPC分类号: F16C7/00 F02B75/32

    摘要: A lightweight crankshaft (1), with eccentric structures, such as con-rods, main bearings, etc., comprises cavities (2, 3, 4, 5, 7, 10, 12) and/or recesses (8) for weight reduction, both in the region of the axis of rotation and isolated therefrom in the region of the eccentric structures. According to the invention at least one cavity is provided (2, 3, 4, 6, 7, 10, 12) in which a stabilizing filler material (5) is located. Said stabilizing filler material can, for example, be a metal foam.

    摘要翻译: 具有偏心结构(例如连杆,主轴承等)的轻质曲轴(1)包括用于减轻重量的空腔(2,3,4,5,7,10,12)和/或凹部(8) 在旋转轴线的区域中,在偏心结构的区域中都与其隔离。 根据本发明,提供至少一个空腔(2,3,4,6,7,10,12),其中定位有稳定的填料材料(5)。 所述稳定填料可以是例如金属泡沫。

    Peptide derivatives of exendin-4
    8.
    发明授权
    Peptide derivatives of exendin-4 有权
    毒蜥外泌肽-4的肽衍生物

    公开(公告)号:US08268781B2

    公开(公告)日:2012-09-18

    申请号:US11712978

    申请日:2007-03-02

    IPC分类号: C07K14/575

    摘要: In the current invention peptides, which are derived from GLP-1 (glucagon-like peptide-1) and exendin-3 and/or exendin-4, are provided which bond to the GLP-receptor and can be used, labeled or unlabeled, for the production of an agent for diagnostic and therapy of benign and malignant diseases, in which GLP-1 receptor expression plays a role.

    摘要翻译: 在本发明中,提供了衍生自GLP-1(胰高血糖素样肽-1)和毒蜥外泌肽-3和/或毒蜥外泌肽-4的肽,其与GLP-受体结合并可以使用,标记或未标记, 用于生产GLP-1受体表达起作用的良性和恶性疾病的诊断和治疗药物。

    Crankshaft comprising a combined gear wheel and method for the production and use of said crankshaft
    9.
    发明申请
    Crankshaft comprising a combined gear wheel and method for the production and use of said crankshaft 审中-公开
    曲轴包括组合的齿轮和用于生产和使用所述曲轴的方法

    公开(公告)号:US20070143997A1

    公开(公告)日:2007-06-28

    申请号:US10573273

    申请日:2004-08-23

    摘要: Motors with high power densities and ignition pressures, for example diesel motors, require crankshafts with combined gear wheels, which can withstand high stresses, especially in their connection areas. As a consequence, forged steel crankshafts, to which tempered gear wheels are fixed by means of screws or welding, are usually employed. The aim of the invention is to provide a method comprising fewer method steps for producing a crankshaft with a combined gear wheel and to provide a crankshaft that has been produced according to said method. To achieve this, the crankshaft comprising the combined gear wheel is cast in one piece. Tempered ductile iron is used as the starting material. The strength and wear resistance is increased locally by peening, or by the application of coatings containing carbide.

    摘要翻译: 具有高功率密度和点火压力的电动机,例如柴油发动机,需要具有组合齿轮的曲轴,其可承受高应力,特别是在其连接区域中。 因此,通常采用通过螺钉或焊接固定回火轮的锻钢曲轴。 本发明的目的是提供一种方法,其包括用于制造具有组合的齿轮的曲轴的方法步骤较少并且提供根据所述方法制造的曲轴。 为了实现这一点,包括组合齿轮的曲轴被铸成一体。 钢化球墨铸铁用作原料。 强度和耐磨性通过喷丸或通过涂覆含碳化物的涂层局部增加。

    Modified minigastrin analogs for oncology applications
    10.
    发明申请
    Modified minigastrin analogs for oncology applications 审中-公开
    用于肿瘤学应用的改良的minigastrin类似物

    公开(公告)号:US20070041903A1

    公开(公告)日:2007-02-22

    申请号:US11206757

    申请日:2005-08-19

    IPC分类号: A61K51/00 C07K7/08

    CPC分类号: A61K51/088 C07K14/595

    摘要: The invention is directed to modified minigastrin analogs. It further relates to labeling such modified minigastrin analogs with metallic radionuclides. The invention further relates to methods for making such novel modified minigastrin analogs, their labeling with metallic radionuclides and their use in oncology applications as in the targeted diagnostic imaging and staging of CCK-2/gastrin-R-positive neoplasms in man with SPECT (technetium-99m), or PET (technetium-94m), or eventually in targeted radionuclide therapy (rhenium-188).

    摘要翻译: 本发明涉及修饰的minigastrin类似物。 它还涉及用金属放射性核素标记这种经修饰的minigastrin类似物。 本发明还涉及制备这种新型修饰的微型中性粒细胞类似物的方法,它们用金属放射性核素的标记及其在肿瘤学应用中的应用,如在用SPECT(锝)的人中CCK-2 /胃泌素-R阳性赘生物的靶向诊断成像和分期 -99m)或PET(锝-94m),或最终在靶向放射性核素治疗(铼-188)中。