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公开(公告)号：US20200297735A1
公开(公告)日：2020-09-24
申请号：US16833186
申请日：2020-03-27
申请人： TherapeuticsMD, Inc.
发明人： Brian A. BERNICK , Thorsteinn THORSTEINSSON , Peter H.R. PERSICANER , Janice Louise CACACE , Frederick D. SANCILIO , Neda IRANI , Julia AMADIO
IPC分类号： A61K31/565 , A61K9/00 , A61K31/57 , A61K47/14
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20200297736A1
公开(公告)日：2020-09-24
申请号：US16833188
申请日：2020-03-27
申请人： TherapeuticsMD, Inc.
发明人： Brian A. BERNICK , Thorsteinn THORSTEINSSON , Peter H.R. PERSICANER , Janice Louise CACACE , Frederick D. SANCILIO , Neda IRANI , Julia AMADIO
IPC分类号： A61K31/565 , A61K9/00 , A61K31/57 , A61K47/14
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20240350514A1
公开(公告)日：2024-10-24
申请号：US18485929
申请日：2023-10-12
申请人： TherapeuticsMD, Inc.
发明人： Brian A. BERNICK , Thorsteinn THORSTEINSSON , Peter H.R. PERSICANER , Janice Louise CACACE , Frederick D. SANCILIO , Neda IRANI , Julia AMADIO
IPC分类号： A61K31/565 , A61K9/00 , A61K31/57 , A61K47/14
CPC分类号： A61K31/565 , A61K9/0036 , A61K31/57 , A61K47/14
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20200147104A1
公开(公告)日：2020-05-14
申请号：US16746434
申请日：2020-01-17
申请人： TherapeuticsMD, Inc.
发明人： Brian A. BERNICK , Thorsteinn THORSTEINSSON , Peter H.R. PERSICANER , Janice Louise CACACE , Frederick D. SANCILIO , Neda IRANI , Julia AMADIO
IPC分类号： A61K31/565 , A61K47/14 , A61K31/57 , A61K9/00
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20230210765A1
公开(公告)日：2023-07-06
申请号：US18046101
申请日：2022-10-12
申请人： TherapeuticsMD, Inc.
IPC分类号： A61K9/00 , A61K31/565 , A61K9/48
CPC分类号： A61K9/0036 , A61K31/565 , A61K9/4858 , A61K47/14
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20230062295A1
公开(公告)日：2023-03-02
申请号：US17705752
申请日：2022-03-28
申请人： TherapeuticsMD, Inc.
发明人： Brian A. BERNICK , Thorsteinn THORSTEINSSON , Peter H.R. PERSICANER , Janice Louise CACACE , Frederick D. SANCILIO , Neda IRANI , Julia AMADIO
IPC分类号： A61K31/565 , A61K9/00 , A61K31/57 , A61K47/14
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20200281849A1
公开(公告)日：2020-09-10
申请号：US16834780
申请日：2020-03-30
申请人： TherapeuticsMD, Inc.
IPC分类号： A61K9/00 , A61K31/565 , A61K9/48
摘要： According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
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公开(公告)号：US20190381068A1
公开(公告)日：2019-12-19
申请号：US16273955
申请日：2019-02-12
申请人： TherapeuticsMD, Inc.
摘要： This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
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公开(公告)号：US20180055855A1
公开(公告)日：2018-03-01
申请号：US15667208
申请日：2017-08-02
申请人： TherapeuticsMD, Inc.
CPC分类号： A61K31/57 , A61K9/4825 , A61K9/4858 , A61K47/14
摘要： This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
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