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公开(公告)号：US10472322B1
公开(公告)日：2019-11-12
申请号：US14065372
申请日：2013-10-28
IPC分类号： C07C279/02 , C07C229/08 , C07C229/24 , C07C229/26 , C07C237/06 , C07C275/16 , C07C323/58 , C07D207/16 , C07D233/64
摘要： A supplement formulation comprising a Nitrate or a Nitrite of an Amino Acid Compound selected from the group consisting of Arginine, Agmatine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornithine, Valine, Aspartic Acid, Cysteine, Glycine, Lysine, Methionine, Proline, Tyrosine, and Phenylalanine is provided. The supplement formulation may be in a dosage form selected from the group consisting of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, and a syrup.
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公开(公告)号：US09353143B1
公开(公告)日：2016-05-31
申请号：US13731549
申请日：2012-12-31
IPC分类号： A61K31/56 , C07J9/00 , C07C53/124 , C07C53/126
CPC分类号： C07J9/00 , A61K9/0019 , A61K9/0053 , A61K9/2004 , A61K9/7023 , A61K31/56 , A61K47/12 , C07C53/124 , C07C53/126
摘要： An ecdysterone compound is described. An ecdysterone compound may include ecdysterone and decanoic acid. An ecdysterone compound may further include ecdysterone and isobutyric acid. An ecdysterone compound may comprise a physiologically active salt or ester of ecdysterone. An ecdysterone compound may further comprise a physiologically active salt or ester of decanoic acid. Alternatively, an ecdysterone compound may include a physiologically active salt or ester of isobutyric acid.
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公开(公告)号：US10646508B1
公开(公告)日：2020-05-12
申请号：US14617515
申请日：2015-02-09
IPC分类号： A61K31/198 , A61K31/05 , A61K31/401 , A61K31/185 , A61K31/375 , A61K31/4172 , A61K33/00 , A61K31/205
摘要： A method of making a composition or a dietary supplement is provided, the method comprising combining a quantity of a Nitrate with a quantity of an Amino Acid Compound, wherein the combining of the Nitrate with the Amino Acid Compound reduces a side effect or toxicity of the Nitrate. Also provided is a method of safely administering to a subject a Nitrate with a reduced side effect or toxicity, the method comprising: combining a quantity of the Nitrate with a quantity of an Amino Acid Compound in a composition or a dietary supplement, wherein the combining of the Nitrate with the Amino Acid Compound reduces the side effect or toxicity of the Nitrate; and safely administering to the subject the composition or dietary supplement comprising the Nitrate with the reduced side effect or toxicity.
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公开(公告)号：US10435356B1
公开(公告)日：2019-10-08
申请号：US14065371
申请日：2013-10-28
IPC分类号： A61K31/198 , C07C279/14 , C07C229/08 , C07C229/24 , C07C229/26 , C07C279/16 , C07C237/06 , C07C279/12 , C07C323/58 , C07D207/16 , C07D233/64
摘要： A composition is disclosed that includes a Nitrate or a Nitrite of an Amino Acid Compound selected from the group consisting of Arginine, Agmatine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornithine, Valine, Aspartic Acid, Cysteine, Glycine, Lysine, Methionine, Proline, Tyrosine, and Phenylalanine, wherein the composition is formulated to deliver an effective amount of the Nitrate or Nitrite of the Amino Acid Compound to prevent the development of nitrate tolerances, to increase bioabsorption of amino acids, to increase the vasodilative characteristics of amino acids, or to increase athletic performance in a human or animal. The composition may be in a dosage form selected from the group consisting of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, and a syrup.
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公开(公告)号：US20170158612A1
公开(公告)日：2017-06-08
申请号：US15438516
申请日：2017-02-21
IPC分类号： C07C227/16 , C07C229/22 , C07C227/42
CPC分类号： C07C227/16 , C07C227/42 , C07C229/22
摘要： Disclosed are salts, such as nitrates, of acetyl-L-carnitine and propionyl-L-carnitine and methods of making the compounds.
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公开(公告)号：US10736916B1
公开(公告)日：2020-08-11
申请号：US14307182
申请日：2014-06-17
IPC分类号： A61K33/00 , A61K31/197 , A61K31/198
摘要： A method for improving athletic or physical performance in a human includes administering to the human a composition or supplement formulation including a single administration of inorganic nitrate (NO3−), a single administration of inorganic nitrite (NO2−), or a combination thereof; and an additive. A method for increasing endurance in a human includes administering to the human a composition or supplement formulation including a single administration of inorganic nitrate (NO3−), a single administration of inorganic nitrite (NO2−), or a combination thereof; and an additive.
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公开(公告)号：US10426750B1
公开(公告)日：2019-10-01
申请号：US14065374
申请日：2013-10-28
IPC分类号： A61K31/198 , C07C279/14 , C07C229/08 , C07C229/24 , C07C229/26 , C07C279/16 , A61K31/21
摘要： A supplement formulation is disclosed that includes a Nitrate or a Nitrite of an Amino Acid Compound selected from the group consisting of Arginine, Agmatine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornithine, Valine, Aspartic Acid, Cysteine, Glycine, Lysine, Methionine, Proline, Tyrosine, and Phenylalanine, wherein the supplement formulation is formulated to deliver an effective amount of the Nitrate or Nitrite of the Amino Acid Compound to prevent the development of nitrate tolerances, to increase bioabsorption of amino acids, to increase the vasodilative characteristics of amino acids, or to increase athletic performance in a human or animal. The supplement formulation may be in a dosage form selected from the group consisting of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, and a syrup.
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公开(公告)号：US10420739B1
公开(公告)日：2019-09-24
申请号：US13917045
申请日：2013-06-13
IPC分类号： A61K31/197 , A23L1/305 , A61K45/06
摘要： The present disclosure provides compositions and methods useful for the treatment of a body weight condition or a thyroid disorder. The compositions induces increased T3 levels while preventing thyroidal atrophy. Also provided are compositions and methods for the treatment of a disease or condition that is estrogen sensitive, estrogen receptor dependent or estrogen receptor mediated such as breast cancer.
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公开(公告)号：US09573883B2
公开(公告)日：2017-02-21
申请号：US14570748
申请日：2014-12-15
IPC分类号： C07C229/22 , C07C227/42 , C07C227/16
CPC分类号： C07C227/16 , C07C227/42 , C07C229/22
摘要： Disclosed are salts, such as nitrates, of acetyl-L-carnitine and propionyl-L-carnitine and methods of making the compounds.
摘要翻译： 公开了乙酰基-L-肉碱和丙酰基-L-肉碱的盐，如硝酸盐，以及制备该化合物的方法。
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公开(公告)号：US20150166466A1
公开(公告)日：2015-06-18
申请号：US14570748
申请日：2014-12-15
IPC分类号： C07C229/22 , C07C227/42 , C07C227/16
CPC分类号： C07C227/16 , C07C227/42 , C07C229/22
摘要： Disclosed are salts, such as nitrates, of acetyl-L-carnitine and propionyl-L-carnitine and methods of making the compounds.
摘要翻译： 公开了乙酰基-L-肉碱和丙酰基-L-肉碱的盐，如硝酸盐，以及制备该化合物的方法。
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