公开(公告)号：US20090258028A1

公开(公告)日：2009-10-15

申请号：US12424489

申请日：2009-04-15

申请人： Thierry Glauser ,  Syed F.A. Hossainy ,  Irina Astafieva ,  Florencia Lim ,  Xinmin Xu ,  Bozena Z. Maslanka ,  Mikael O. Trollsas ,  Michael H. Ngo

发明人： Thierry Glauser ,  Syed F.A. Hossainy ,  Irina Astafieva ,  Florencia Lim ,  Xinmin Xu ,  Bozena Z. Maslanka ,  Mikael O. Trollsas ,  Michael H. Ngo

IPC分类号： A61K38/00 ,  A61K39/395

CPC分类号： A61L31/10 ,  A61L31/16 ,  A61L2300/25 ,  A61L2300/252 ,  A61L2300/416 ,  A61L2300/606 ,  C08L33/14 ,  C08L75/04

摘要： This invention is generally related to methods of forming coatings for implantable medical devices, such as drug delivery vascular stents. The methods are for forming coatings to control the release of a peptide such as RGD, and a hydrophobic drug. Both single layer and multiple layer coating constructs are encompassed in the various embodiments of the present invention.

摘要翻译： 本发明通常涉及形成用于可植入医疗装置（例如药物输送血管支架）的涂层的方法。 所述方法用于形成涂层以控制肽如RGD和疏水性药物的释放。 单层和多层涂层构造都包含在本发明的各种实施方案中。

公开(公告)号：US6117106A

公开(公告)日：2000-09-12

申请号：US419614

申请日：1999-10-14

申请人： Lawrence D. Wasicek ,  Yen Chan ,  Mina W. B. Chow ,  Ketan P. Muni ,  Bozena Z. Maslanka

发明人： Lawrence D. Wasicek ,  Yen Chan ,  Mina W. B. Chow ,  Ketan P. Muni ,  Bozena Z. Maslanka

IPC分类号： A61M25/00 ,  A61M29/02

CPC分类号： A61M25/104 ,  A61M25/0052 ,  A61M2025/0004 ,  A61M2025/1079 ,  A61M2025/1097 ,  A61M25/0053

摘要： A perfusion dilatation catheter is disclosed which has an improved distal catheter shaft portion with a tubular member extending within the balloon provided with an expanded coil support incorporated within the wall of the tubular member. The coil is preferably closer to the inner surface than the outer surface of the tubular member. Also disclosed are improved catheter shaft sections in a perfusion portion proximal to the balloon, one with a reinforced inflation tube depending into the guidewire lumen and another having three separate lumens, a central guidewire lumen and a pair of inflation lumens on opposing sides of the tubular structure defining the guidewire lumen.

摘要翻译： 公开了一种灌注扩张导管，其具有改进的远端导管轴部分，其具有在球囊内延伸的管状构件，该管状构件设置有并入管状构件的壁内的扩张的线圈支架。 线圈优选地比管状构件的外表面更靠近内表面。 还公开了在靠近气囊的灌注部分中的改进的导管轴部分，一个具有依赖于导丝管腔的增强的充气管，另一个具有三个独立的腔，中心导丝腔和一对在管的相对侧上的充气腔 限定导丝管腔的结构。