公开(公告)号：US06592901B2

公开(公告)日：2003-07-15

申请号：US09977785

申请日：2001-10-15

申请人： Thomas Durig ,  Ronald Haywood Hall ,  Richard A. Salzstein

发明人： Thomas Durig ,  Ronald Haywood Hall ,  Richard A. Salzstein

IPC分类号： A61K914

CPC分类号： A61K9/2054

摘要： A pharmaceutical dosage form composition is composed of an ethylcellulose that has an ethoxyl range lower limit of 49.6%, an a viscosity of less than 53 cps and at least one active pharmaceutical ingredient. This dosage form is highly compressible and compactible forming harder tables or pellets with better release retardation than comparable prior art tablets.

摘要翻译： 药物剂型组合物由乙氧基范围下限为49.6％，粘度小于53cps的乙基纤维素和至少一种活性药物成分组成。 该剂型是高度可压缩和可压缩的，形成具有比现有技术的片剂更好的释放阻滞的较硬的桌子或丸剂。

公开(公告)号：US5522904A

公开(公告)日：1996-06-04

申请号：US135484

申请日：1993-10-13

申请人： James M. Moran ,  Richard A. Salzstein ,  Isaac M. Daniel ,  Douglas S. Cairns ,  Daniel B. Smith

发明人： James M. Moran ,  Richard A. Salzstein ,  Isaac M. Daniel ,  Douglas S. Cairns ,  Daniel B. Smith

IPC分类号： A61F2/00 ,  A61F2/30 ,  A61F2/36 ,  A61L27/44 ,  B29C70/20 ,  A61F2/32

CPC分类号： A61L27/443 ,  A61F2/30965 ,  A61F2/3609 ,  B29C70/202 ,  A61F2/3662 ,  A61F2002/30009 ,  A61F2002/30014 ,  A61F2002/30332 ,  A61F2002/30952 ,  A61F2002/30957 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/365 ,  A61F2220/0033 ,  A61F2250/0018 ,  A61F2250/0028 ,  B29C2793/009 ,  B29L2031/7532

摘要： A femoral implant for a hip prosthesis includes a shaft oriented in a longitudinal direction and a neck extending from said shaft at an acute angle .theta. to the longitudinal direction. The implant includes a plurality of layers of fibers in a matrix, wherein the fibers are substantially unidirectional in each respective layer. The implant is made from a stack of layers of the matrix so that the direction of fibers is unbalanced. At least 50% of the fibers are oriented in the .theta. direction and the remainder of said fibers are oriented in directions other than the .theta. angle.

摘要翻译： 用于髋关节假体的股骨植入物包括沿纵向定向的轴和从所述轴以锐角θ延伸到纵向方向的颈部。 植入物包括矩阵中的多层纤维，其中纤维在每个相应层中基本上是单向的。 植入物由矩阵层的堆叠制成，使得纤维的方向不平衡。 至少50％的纤维在θ方向上定向，并且所述纤维的其余部分取向于θ角以外的方向。

公开(公告)号：US5163962A

公开(公告)日：1992-11-17

申请号：US574684

申请日：1990-08-30

申请人： Richard A. Salzstein ,  Guy R. Toombes

发明人： Richard A. Salzstein ,  Guy R. Toombes

IPC分类号： A61F2/32 ,  A61F2/00 ,  A61F2/30 ,  A61F2/36 ,  A61L27/00 ,  A61L27/44

CPC分类号： A61F2/36 ,  A61F2/30965 ,  A61L27/443 ,  A61F2/3662 ,  A61F2002/30009 ,  A61F2002/30332 ,  A61F2002/3625 ,  A61F2002/365 ,  A61F2220/0033 ,  A61F2250/0028

摘要： Disclosed is an improvement in a femoral implant for a hip prosthesis involving a longitudinal shaft having a neck extending therefrom at an acute angle .theta. to the longitudinal direction made of layers of carbon fiber in a polymeric matrix, each layer containing unidirectional fibers and the layers arranged such that carbon fibers are oriented in the longitudinal direction and the .+-..theta. direction. The improvement involves balancing at least 50% of the layers in the .+-..theta. direction.