公开(公告)号：US4174352A

公开(公告)日：1979-11-13

申请号：US903425

申请日：1978-05-08

申请人： Thomas H. Fisher ,  William Dowd

发明人： Thomas H. Fisher ,  William Dowd

IPC分类号： C07C45/27 ,  C07C45/00

CPC分类号： C07C45/27

摘要： A process for preparing an allylic or an aromatic aldehyde, such as acrolein or benzaldehyde, the process comprising contacting in a basic, liquid, biphasic mixture and at reactive conditions an allylic halide or a halomethylated aromatic, such as allyl or benzyl chloride, with a divalent chromate ion, is improved by contacting the allylic halide or halomethylated aromatic with the divalent chromate ion in the presence of a catalytic amount of a quaternary ammonium and/or phosphonium salt, such as tetra-n-butylammonium chloride. The improved process is faster, cleaner and more complete than the process of the prior art.

摘要翻译： 一种制备烯丙基或芳族醛如丙烯醛或苯甲醛的方法，该方法包括在碱性，液体，双相混合物中和在反应条件下使烯丙基卤或卤代甲基化的芳族化合物如烯丙基或苄基氯与 二价铬酸根离子通过在催化量的季铵和/或鏻盐如四正丁基氯化铵存在下使烯丙基卤化物或卤代甲基化的芳族化合物与二价铬酸根离子接触来改善。 改进的方法比现有技术的方法更快，更清洁并且更完整。

公开(公告)号：US4144265A

公开(公告)日：1979-03-13

申请号：US925336

申请日：1978-07-17

申请人： William Dowd ,  Thomas H. Fisher

发明人： William Dowd ,  Thomas H. Fisher

IPC分类号： C07C255/32 ,  C07C120/04 ,  C07C121/66

CPC分类号： C07C255/32

摘要： Quaternary ammonium salts, such as methyl tributyl ammonium chloride, are novel catalysts in a nitrile-forming reaction which comprises stirring together aqueous sodium cyanide and the undistilled m-trifluoromethyl benzyl chloride product of the reaction of chloromethyl methyl ether, chlorosulfonic acid and trifluoromethyl benzene from which chloromethyl ether impurities, methanol, water and some of the unreacted trifluoromethyl benzene are removed. The process is conducted under alkaline conditions in a two-phase liquid reaction medium. m-Trifluoromethyl benzyl nitrile is prepared in excellent yields and purity.

摘要翻译： 季铵盐如甲基三丁基氯化铵是腈形成反应中的新型催化剂，其中包括将氯甲基甲基醚，氯磺酸和三氟甲基苯反应的氰化钠水溶液与未蒸馏的三氟甲基苄基氯产物一起搅拌 除去氯甲基醚杂质，甲醇，水和一些未反应的三氟甲基苯。 该方法在碱性条件下在两相液体反应介质中进行。 以三氟甲基苄腈制备出优异的产率和纯度。