公开(公告)号：US20100172956A1

公开(公告)日：2010-07-08

申请号：US12445190

申请日：2007-10-12

Applicant: Thomas Kalili

Inventor： Thomas Kalili

IPC: A61K9/70 ,  A61K47/36

CPC classification number: A61K9/006 ,  A61K9/7007

Abstract: The invention relates to a dissolving strip for drug delivery providing a generally inert water soluble base material attached to the maxillary molars in order to deliver a therapeutic material upon activation by the parotid and other oral salivary glands. The composition of the dissolving strip is a generally inert base material, such as pullulan. The pullulan is impregnated with a therapeutic material to form a solid mixture to carry the therapeutic agent. The dissolving strip has sufficient flexibility to adhere to the 1-4 maxillary molars and acts as a reservoir to deliver therapeutic agents, such as an anti-smoking formula, a diet formula, a sexual enhancement formula, an oral freshness formula, prescription drugs, non-prescription drugs, herbs, or vitamins, or any combination of the previously listed. The dissolving strip is capable of delivering the therapeutic agents in a sustained or time released fashion.

Abstract translation: 本发明涉及用于药物递送的溶解条，其提供连接到上颌磨牙的通常为惰性的水溶性基材，以便在由腮腺和其它口腔唾液腺激活时递送治疗物质。 溶解条的组成是通常为惰性的基材，例如支链淀粉。 用治疗材料浸渍支链淀粉以形成固体混合物以携带治疗剂。 溶解条具有足够的柔韧性以粘附到1-4上颌磨牙上，并作为储存器递送治疗剂，例如抗吸烟配方，饮食配方，性增强配方，口腔新鲜配方，处方药， 非处方药，草药或维生素，或以前列出的任何组合。 溶解条能够以持续或时间释放的方式递送治疗剂。

公开(公告)号：US20110020761A1

公开(公告)日：2011-01-27

申请号：US12814725

申请日：2010-06-14

Applicant: Thomas Kalili

Inventor： Thomas Kalili

IPC: A61C7/08 ,  B23P13/00 ,  A61C9/00

CPC classification number: A61C7/08 ,  A61C2201/007 ,  Y10T29/49568

Abstract: An invisible removable orthodontic repositioning appliance with a lower modulus inner lining for systematically aligning teeth from an initial tooth arrangement to a final tooth arrangement while minimizing propensity for root and bone resorption due to the lower modulus is disclosed. The aligning of the teeth may be accomplished by taking impressions at various intervals for greater accuracy in the event of a distorted impression. Patient impression and/or model may then be digitally scanned. Using 3D software, tooth position may be incrementally modified toward idealized position and associated stress analyzed. Final modified model and associated appliance may be fabricated for orthodontic movement using 3D printing. Each appliance may be numerically identified to maintain uniformity of application from start of treatment to completion. The forces required for the alignment may be from polymeric material used to fabricate the orthodontic appliances, the shape memory alloy, and/or micro-implants to accomplish optimal tooth movement.

Abstract translation: 公开了一种具有较低模量内衬的不可见的可移除的正畸矫正器具，用于从初始牙齿布置到最终牙齿布置的系统地对准牙齿，同时由于较低的模量而使根和骨吸收的倾向最小化。 可以通过在发生失真的印象的情况下以各种间隔获得印象以获得更高精度来实现齿的对准。 然后可以对患者印象和/或模型进行数字扫描。 使用3D软件，牙齿位置可以逐渐改变为理想位置和相关应力分析。 可以使用3D打印来制造用于正畸运动的最终修改的模型和相关联的装置。 每个器具可以被数字识别，以保持从开始处理到完成的应用的一致性。 对准所需的力可以来自用于制造正畸器具的聚合材料，形状记忆合金和/或微型植入物，以实现最佳牙齿移动。