公开(公告)号：US20100203640A1

公开(公告)日：2010-08-12

申请号：US12663239

申请日：2008-06-05

申请人： Thomas Wekerle ,  Rudolf Valenta ,  Ulrike Baranyi ,  Birgit Linhart ,  Nina Pilat ,  Jessamyn Bagley ,  John Iacomini ,  Martina Gattringer

发明人： Thomas Wekerle ,  Rudolf Valenta ,  Ulrike Baranyi ,  Birgit Linhart ,  Nina Pilat ,  Jessamyn Bagley ,  John Iacomini ,  Martina Gattringer

IPC分类号： C12N15/63 ,  C12N5/10

CPC分类号： C12N5/0647 ,  A61K38/16 ,  A61K38/17 ,  A61K39/35 ,  A61K2039/5156 ,  A61K2039/53 ,  C07K16/16

摘要： The present invention relates to a method for inducing specific long-lasting robust immunological tolerance towards at least one polypeptide derived from at least one allergen by transplanting a hematopoietic (stem) cell which is produced to display the said at least one polypeptide derived from at least one allergen.

摘要翻译： 本发明涉及一种通过移植造血干细胞（stem）来诱导对至少一种衍生自至少一种变应原的至少一种多肽的强力免疫耐受性的方法，所述造血细胞（干细胞）被产生以显示所述至少一种至少一种多肽 一种过敏原