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1.发明申请Combination of unsaponifiable lipids combined with polyphenols and/or catechins for the protection, treatment and repair of cartilage in joints of humans and animals 审中-公开将不皂化脂质与多酚和/或儿茶素组合用于人和动物关节中软骨的保护，治疗和修复公开(公告)号：US20080176935A1
公开(公告)日：2008-07-24
申请号：US11889060
申请日：2007-08-08
IPC分类号： A61K31/353 , A61P19/00
CPC分类号： A61K31/353 , A61K9/0053 , A61K31/05 , A61K31/685 , A61K36/48 , A61K36/54 , A61K36/82 , A61K2300/00
摘要： The present invention relates to a composition and a kit for the protection, treatment and repair of cartilage in humans and animal joints. The composition or kit contains a combination of unsaponifiable lipids together with one or more of polyphenols and/or catechins. Preferably, the composition or kit contains avocado:soybean unsaponifiables (ASU) and green tea
摘要翻译： 本发明涉及用于人和动物关节软骨的保护，治疗和修复的组合物和试剂盒。 组合物或试剂盒包含不皂化脂质与多酚和/或儿茶素中的一种或多种的组合。 优选地，组合物或试剂盒含有鳄梨：大豆不皂化物（ASU）和绿茶
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2.发明授权公开(公告)号：US08808770B2
公开(公告)日：2014-08-19
申请号：US12780642
申请日：2010-05-14
CPC分类号： A61K31/353 , A61K9/0053 , A61K31/05 , A61K31/685 , A61K36/48 , A61K36/54 , A61K36/82 , A61K2300/00
摘要： The present invention relates to a composition and a kit for the protection, treatment and repair of cartilage in humans and animal joints. The composition or kit contains a combination of unsaponifiable lipids together with one or more of polyphenols and/or catechins. Preferably, the composition or kit contains avocado:soybean unsaponifiables (ASU) and green tea.
摘要翻译： 本发明涉及用于人和动物关节软骨的保护，治疗和修复的组合物和试剂盒。 组合物或试剂盒包含不皂化脂质与多酚和/或儿茶素中的一种或多种的组合。 优选地，组合物或试剂盒含有鳄梨：大豆不皂化物（ASU）和绿茶。
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3.发明申请Combination of unsaponifiable lipids combined with polyphenols and/or catechins for the protection, treatment and repair of cartilage in joints of humans and animals 审中-公开将不皂化脂质与多酚和/或儿茶素组合用于人和动物关节中软骨的保护，治疗和修复公开(公告)号：US20060029685A1
公开(公告)日：2006-02-09
申请号：US11192362
申请日：2005-07-29
CPC分类号： A61K31/353 , A61K9/0053 , A61K31/05 , A61K31/685 , A61K36/48 , A61K36/54 , A61K36/82 , A61K2300/00
摘要： The present invention relates to a composition and a kit for the protection, treatment and repair of cartilage in humans and animal joints. The composition or kit contains a combination of unsaponifiable lipids together with one or more of polyphenols and/or catechins. Preferably, the composition or kit contains avocado:soybean unsaponifiables (ASU) and green tea.
摘要翻译： 本发明涉及用于人和动物关节软骨的保护，治疗和修复的组合物和试剂盒。 组合物或试剂盒包含不皂化脂质与多酚和/或儿茶素中的一种或多种的组合。 优选地，组合物或试剂盒含有鳄梨：大豆不皂化物（ASU）和绿茶。
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4.发明申请STABILIZED PENTOSAN POLYSULFATE (PPS) FORMULATIONS AND METHODS OF ANALYZING THEM 审中-公开稳定的蓬松多糖（PPS）制剂及其分析方法公开(公告)号：US20110212914A1
公开(公告)日：2011-09-01
申请号：US13036995
申请日：2011-02-28
IPC分类号： A61K31/715 , C07H5/10 , A61P19/02 , A61P25/00 , A61P31/18 , A61P17/02 , A61P7/02 , A61P9/10 , G01N27/447
CPC分类号： A61K9/0019 , A61K9/19 , A61K31/7008 , A61K31/7024 , A61K31/728 , A61K31/737 , A61K47/02 , A61K47/14 , A61K47/183 , A61K2300/00
摘要： Various pentosan polysulfate (PPS) formulations useful for treatment of osteoarthritis, interstitial cystitis, and other conditions of mammals are provided. These formulations showed improved resistance to degradation and discoloration and improved stability at physiological pH, even after sterilization. Capillary electrophoresis analysis of these formulations indicates that various formulations remain stable under conditions that caused degradation of PPS in prior art PPS formulations.
摘要翻译： 提供了可用于治疗骨关节炎，间质性膀胱炎和哺乳动物其他条件的各种戊聚糖多硫酸酯（PPS）制剂。 这些制剂即使在灭菌后也显示出改善的降解和变色性，并且改善了生理pH下的稳定性。 这些制剂的毛细管电泳分析表明，在现有技术PPS制剂中导致PPS降解的条件下，各种制剂保持稳定。
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5.发明申请Stabilized pentosan polysulfate (PPS) formulations and methods of analyzing them 审中-公开稳定的戊聚糖多硫酸酯（PPS）配方及其分析方法公开(公告)号：US20070243218A1
公开(公告)日：2007-10-18
申请号：US11730742
申请日：2007-04-03
IPC分类号： A61K31/7024 , A61K31/7008 , A61K9/00
CPC分类号： A61K9/0019 , A61K9/19 , A61K31/7008 , A61K31/7024 , A61K31/728 , A61K31/737 , A61K47/02 , A61K47/14 , A61K47/183 , A61K2300/00
摘要： Various pentosan polysulfate (PPS) formulations useful for treatment of osteoarthritis, interstitial cystitis, and other conditions of mammals are provided. These formulations showed improved resistance to degradation and discoloration and improved stability at physiological pH, even after sterilization. Capillary electrophoresis analysis of these formulations indicates that various formulations remain stable under conditions that caused degradation of PPS in prior art PPS formulations.
摘要翻译： 提供了可用于治疗骨关节炎，间质性膀胱炎和哺乳动物其他条件的各种戊聚糖多硫酸酯（PPS）制剂。 这些制剂即使在灭菌后也显示出改善的降解和变色性，并且改善了生理pH下的稳定性。 这些制剂的毛细管电泳分析表明，在现有技术PPS制剂中导致PPS降解的条件下，各种制剂保持稳定。
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