专利检索 ap:("Tomio Takeuchi" OR "Kazuo Umezawa" OR "Sakino To-E" OR "Naoki Matsumoto" OR "Tsutomu Sawa" OR "Takeo Yoshioka" OR "Naoki Agata" OR "Shin-ichi Hirano" OR "Kunio Isshiki") AND inv:"Sakino To-E" 第 1 页

1.

发明授权
Salicylamide derivatives 失效
标题翻译：水杨酰胺衍生物

公开(公告)号：US06566394B1

公开(公告)日：2003-05-20

申请号：US10049158

申请日：2002-05-30

申请人： Tomio Takeuchi , Kazuo Umezawa , Sakino To-E , Naoki Matsumoto , Tsutomu Sawa , Takeo Yoshioka , Naoki Agata , Shin-ichi Hirano , Kunio Isshiki

发明人： Tomio Takeuchi , Kazuo Umezawa , Sakino To-E , Naoki Matsumoto , Tsutomu Sawa , Takeo Yoshioka , Naoki Agata , Shin-ichi Hirano , Kunio Isshiki

IPC分类号： A61K31336

CPC分类号： C07D303/36 , C07C237/38 , C07C237/40

摘要： Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as anti-inflammatory agents and immunosuppressive agents which exert an effect of inhibiting the activation of NF-&kgr;B with little side effects.

摘要翻译： 由式（1a）和（1b）表示的水杨酰胺衍生物; 中间体在其生产中; 其制造方法; 和含有与活性成分相同的药物。由式（1a）和（1b）表示的水杨酰胺衍生物可用作具有抑制NF-κB活化的副作用的抗炎剂和免疫抑制剂。