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公开(公告)号：US08071126B2
公开(公告)日：2011-12-06
申请号：US12666435
申请日：2008-03-19
Applicant: Toru Sekiguchi , Kaname Nakahara , Toru Watanabe
Inventor： Toru Sekiguchi , Kaname Nakahara , Toru Watanabe
CPC classification number: A61K9/703 , A61F2013/00646 , A61K9/7038 , A61K9/7084 , A61L15/44 , A61L15/58 , A61L2300/256 , A61L2300/406 , A61L2300/41 , A61L2300/428 , A61L2300/608 , A61M35/006 , Y10T428/1495
Abstract: A percutaneous absorption type patch adapted to be applied to a skin surface of a patient. The percutaneous absorption type patch comprises: a stratum-corneum release member constituted from a sheet-like first supporting substrate and a pressure-sensitive adhesive layer laminated on the first supporting member; a medicinal-components administration member constituted from a sheet-like second supporting substrate, a medicinal-components retention layer laminated on the second supporting substrate, and a protect layer laminated on the medicinal-components retention layer; and a sheet-like handling member interposed between the stratum-corneum release member and the medicinal-components administration member. An edge portion of the handling member is coupled to or integrated with both the first supporting substrate and the protect layer. Operations of peeling the stratum-corneum release member from the skin surface of the patient and peeling the protect layer from the medicinal-components retention layer are carried out at a time by pulling the handling member toward an operating direction.
Abstract translation: 适合施用于患者皮肤表面的经皮吸收型贴剂。 经皮吸收型贴片包括：由片状第一支撑基板和层叠在第一支撑部件上的压敏粘合剂层构成的角质层释放部件; 由片状第二支撑基板，层叠在第二支撑基板上的药物保持层和层叠在药剂保持层上的保护层构成的药物成分给药部件， 以及插入在角质层释放构件和药物成分给药构件之间的片状处理构件。 处理构件的边缘部分与第一支撑衬底和保护层两者耦合或一体化。 通过沿着操作方向拉动处理构件，一次执行从患者皮肤表面剥离角质层释放构件并从保护层剥离保护层的操作。
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公开(公告)号：US20110251561A1
公开(公告)日：2011-10-13
申请号：US13055378
申请日：2009-07-27
Applicant: Akinori Inou , Masahiro Takigawa , Toru Sekiguchi , Kaname Nakahara , Toru Watanabe
Inventor： Akinori Inou , Masahiro Takigawa , Toru Sekiguchi , Kaname Nakahara , Toru Watanabe
CPC classification number: A61M37/0015 , A61M2037/0023 , A61M2037/0046
Abstract: The transdermal administration device of the present invention includes: a device body including a needle form body, which includes a plurality of microneedles formed on a surface thereof and is provided with a fluid passage hole through the front surface to a back surface thereof, and a medical fluid filling section for providing a medical fluid to the back surface of the needle form body; a stratum corneum peeling system; and a connection section for connecting the device body and the stratum corneum peeling system, where the stratum corneum peeling system is connected to the device body by the connection section such that the microneedles of the needle form body of the device body are positioned in an area of a skin surface in which a stratum corneum is peeled by the stratum corneum peeling system.
Abstract translation: 本发明的透皮给药装置包括：装置主体，其包括针形体，其包括在其表面上形成的多个微针，并且在其前表面的后表面上设置有流体通道孔， 药液填充部，用于向针形体的后表面提供医用流体; 角质层剥离系统; 以及用于连接装置主体和角质层剥离系统的连接部分，其中角质层剥离系统通过连接部分连接到装置主体，使得装置主体的针形体的微针位于一个区域 的皮肤表面，其中角质层被角质层剥离系统剥离。
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公开(公告)号：US20100189751A1
公开(公告)日：2010-07-29
申请号：US12666435
申请日：2008-03-19
Applicant: Toru Sekiguchi , Kaname Nakahara , Toru Watanabe
Inventor： Toru Sekiguchi , Kaname Nakahara , Toru Watanabe
IPC: A61K9/70
CPC classification number: A61K9/703 , A61F2013/00646 , A61K9/7038 , A61K9/7084 , A61L15/44 , A61L15/58 , A61L2300/256 , A61L2300/406 , A61L2300/41 , A61L2300/428 , A61L2300/608 , A61M35/006 , Y10T428/1495
Abstract: A percutaneous absorption type patch adapted to be applied to a skin surface of a patient. The percutaneous absorption type patch comprises: a stratum-corneum release member constituted from a sheet-like first supporting substrate and a pressure-sensitive adhesive layer laminated on the first supporting member; a medicinal-components administration member constituted from a sheet-like second supporting substrate, a medicinal-components retention layer laminated on the second supporting substrate, and a protect layer laminated on the medicinal-components retention layer; and a sheet-like handling member interposed between the stratum-corneum release member and the medicinal-components administration member. An edge portion of the handling member is coupled to or integrated with both the first supporting substrate and the protect layer. Operations of peeling the stratum-corneum release member from the skin surface of the patient and peeling the protect layer from the medicinal-components retention layer are carried out at a time by pulling the handling member toward an operating direction.
Abstract translation: 适合施用于患者皮肤表面的经皮吸收型贴剂。 经皮吸收型贴片包括：由片状第一支撑基板和层叠在第一支撑部件上的压敏粘合剂层构成的角质层释放部件; 由片状第二支撑基板，层叠在第二支撑基板上的药物保持层和层叠在药剂保持层上的保护层构成的药物成分给药部件， 以及插入在角质层释放构件和药物成分给药构件之间的片状处理构件。 处理构件的边缘部分与第一支撑衬底和保护层两者耦合或一体化。 通过沿着操作方向拉动处理构件，一次执行从患者皮肤表面剥离角质层释放构件并从保护层剥离保护层的操作。
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公开(公告)号：US20120121350A1
公开(公告)日：2012-05-17
申请号：US13297404
申请日：2011-11-16
Applicant: Kazunori Kitamori , Toru Sekiguchi
Inventor： Kazunori Kitamori , Toru Sekiguchi
IPC: B23B51/02
CPC classification number: B23B51/02 , B23B2222/04 , B23B2226/275 , B23B2251/04 , B23B2251/14 , Y10T408/89 , Y10T408/9097
Abstract: A drill capable of suppressing inter-layer peeling (delamination) while keeping hole diameter accuracy even if the number of holed to be worked increases is provided. The drill includes a first flank which has a ridge line forming a cutting edge, a second flank which is adjacent to the first flank and has a ridge line forming a land portion, and a third flank which is adjacent to the first flank and has a ridge line forming a chisel edge. The drill further includes a fourth flank which is surrounded by a ridge line forming the first flank, a ridge line forming the third flank, and a trough line forming the second flank
Abstract translation: 提供能够抑制层间剥离（分层）同时保持孔直径精度的钻孔，即使要加工的孔数增加。 钻头包括具有形成切削刃的棱线的第一侧面，与第一侧面相邻并具有形成陆部的棱线的第二侧面和与第一侧面相邻的第三侧面，并且具有 脊线形成凿边。 所述钻头还包括第四侧面，所述第四侧面被形成所述第一侧面的脊线包围，形成所述第三侧面的脊线和形成所述第二侧面的槽线
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公开(公告)号：US06719501B2
公开(公告)日：2004-04-13
申请号：US09976272
申请日：2001-10-15
Applicant: Toru Sekiguchi , Yuu Kagiya , Yasushi Goshima
Inventor： Toru Sekiguchi , Yuu Kagiya , Yasushi Goshima
IPC: B23B2714
CPC classification number: C23C30/005 , B23C5/10 , B23C2210/202 , B23C2210/203 , B23C2224/36 , B23C2226/18 , B23C2228/10 , Y10T407/1966 , Y10T407/27
Abstract: A cemented carbide end mill has three or more cutting edges formed on its periphery and flutes each provided between adjacent cutting edges. The land width of each cutting edge and the flute width has a ratio of 1:1.5 to 1:4. Each flute has a helix angle of 35°-60° and, when viewed in a cross section perpendicular to the end mill axis, is in a shape smoothly concave radially inwardly. The core of the end mill has a diameter which is 62%-68% of the outer diameter of the end mill. The cutting edges have a base material of ultra-fine cemented carbide and are coated with a titanium-aluminum nitride hard film. The end mill is good at chip discharging in groove cutting and provides less inclination of cut grooves and less corner wear of the end mill.
Abstract translation: 硬质合金立铣刀具有在其周边上形成的三个或更多个切削刃和各自设置在相邻切削刃之间的槽纹。 每个切削刃的刃宽和槽宽的比例为1:1.5至1:4。 每个槽具有35°-60°的螺旋角，并且当在垂直于端铣刀轴线的横截面中观察时，其形状呈径向向内平滑地凹陷。 立铣刀的芯部的直径为端铣刀的外径的62％-68％。 切削刃具有超细硬质合金的基材，并涂覆有钛 - 氮化铝硬质膜。 端铣刀在槽切削中具有良好的切屑排放，并且提供切割槽的较小倾斜度和较少的端铣刀的角磨损。
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Patent Agency Ranking6.发明授权Focus servo circuit for a magneto-optical disk recording and reproducing apparatus 失效用于磁光盘记录和再现装置的聚焦伺服电路
公开(公告)号：US5263009A
公开(公告)日：1993-11-16
申请号：US736981
申请日：1991-07-29
Applicant: Yoshihiro Sasaki , Toru Sekiguchi
Inventor： Yoshihiro Sasaki , Toru Sekiguchi
IPC: G11B11/10 , G11B7/085 , G11B7/09 , G11B11/105 , G11B7/00
CPC classification number: G11B11/10576 , G11B7/0945
Abstract: An apparatus for optically recording/reproducing data to/from a disc including a focus servo circuit which initially sets an objective lens of an optical head to a predetermined setting. This predetermined setting is such that a laser beam passing through the lens is focused on the disc at a point inside of the disc in the thickness direction. Then, the focus servo circuit fine tunes the objective lens position until the laser beam is focused onto a recording film located inside of the disc.
Abstract translation: 一种用于向/从光盘记录/再现数据的装置，包括聚焦伺服电路，其将光头的物镜初始设定为预定设定。 该预定设定使得通过透镜的激光束在厚度方向盘的内侧聚焦在光盘上。 然后，聚焦伺服电路微调物镜位置，直到激光束聚焦到位于光盘内部的记录膜上。
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7.发明授权
公开(公告)号：US5040163A
公开(公告)日：1991-08-13
申请号：US472856
申请日：1990-01-31
Applicant: Yoshihiro Sasaki , Toru Sekiguchi
Inventor： Yoshihiro Sasaki , Toru Sekiguchi
IPC: G11B7/125 , G11B11/105 , H01S5/042
CPC classification number: G11B7/126 , G11B11/10541
Abstract: A laser beam control circuit for an optical recording/reproducing apparatus, which controls the intensity of a laser beam striking a magneto-optical disc. The control circuit controls the injection current to a laser diode to provide high intensity for recording and low intensity for reproducing, providing a smooth transition between the high and low intensity states, and avoiding any excessive transition current. The control circuit monitors the output power of the laser diode and maintains it at a first value in the reproducing mode and a second value in the recording mode, and further controls the output power so that even during switching, the output power does not exceed the second level. This is done by supplying a compensating reference voltage to the recording power control loop during the reproducing mode, so that the output of the recording error amplifier does not change abruptly when the operating mode is switched to the recording mode.
Abstract translation: 一种用于光学记录/再现装置的激光束控制电路，其控制激光束撞击磁光盘的强度。 控制电路控制到激光二极管的注入电流以提供高强度的记录和低强度的再现，提供高强度状态和低强度状态之间的平滑过渡，并避免任何过度的过渡电流。 控制电路监视激光二极管的输出功率，并将其保持在再现模式下的第一值，并在记录模式下保持第二值，并进一步控制输出功率，使得即使在切换期间，输出功率也不会超过 二级 这通过在再现模式期间向记录功率控制环路提供补偿参考电压来完成，使得当操作模式切换到记录模式时，记录误差放大器的输出不会突然改变。
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公开(公告)号：US4951154A
公开(公告)日：1990-08-21
申请号：US149565
申请日：1988-01-28
Applicant: Toru Sekiguchi , Yoshihiro Sasaki
Inventor： Toru Sekiguchi , Yoshihiro Sasaki
CPC classification number: H04N5/94 , G11B11/10515 , G11B11/10543 , G11B11/10597 , G11B20/025 , G11B27/36 , G11B33/10 , G11B7/0948 , H04N5/85 , H04N5/93
Abstract: Disclosed is a magneto-optic recording/reproducing apparatus capable of detecting small size defects in a magneto-optic recording disk in the order of tens of microns in size, and capable of reliably compensating for signal defects of a video image recorded on the disk. In the apparatus first and second photodetectors are provided for detecting information signals of two luminous fluxes into which a luminous flux emitted from a laser oscillator is divided by light splitting means. The photodetectors are arranged on the part of light reflected or emitted by the surface of a magneto-optic recording medium when it is irradiated with the luminous flux from the laser oscillator. According to the invention, the signals produced by the photodetectors are processed to produce a highly sensitive defect signal or a plurality of highly sensitive defect signals which may be summed together.
Abstract translation: 公开了一种磁光记录/再现装置，其能够检测大小几十微米级的磁光记录盘中的小尺寸缺陷，并能够可靠地补偿记录在盘上的视频图像的信号缺陷。 在装置中，第一和第二光电探测器用于检测从激光振荡器发射的光束被光分解装置分开的两个光束的信息信号。 光电探测器被布置在由光磁记录介质的表面反射或发射的光的部分上，当它被来自激光振荡器的光通量照射时。 根据本发明，由光电检测器产生的信号被处理以产生高灵敏度的缺陷信号或多个高灵敏度缺陷信号，这些信号可以相加在一起。
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公开(公告)号：US4520410A
公开(公告)日：1985-05-28
申请号：US470667
申请日：1983-02-28
Applicant: Toru Sekiguchi , Isao Sanguu
Inventor： Toru Sekiguchi , Isao Sanguu
Abstract: A scan tracking apparatus for a helical scan tape recorder, comprising a movable tape head (11), a detector (13) detecting the envelope of the tape signal to produce a reproduced signal, sampling means (15) for sampling the reproduced signal at fixed points of the helical scan, memory (17) for storing the reproduced signal and correction signals from different tracks of the helical scan, computation means (2) for computing a correction signal to return the tape head to the center of the track, a sawtooth generator (2, 4) for producing a signal related to the tape speed (v), and a head driving mechanism (9) for moving the tape head in response to the sawtooth and correction signals.
Abstract translation: 一种用于螺旋扫描磁带录像机的扫描跟踪装置，包括可移动磁带头（11），检测磁带信号的包络以产生再现信号的检测器（13），用于对固定的再现信号进行采样的采样装置（15） 螺旋扫描的点，用于存储重放信号的存储器（17）和来自螺旋扫描的不同轨道的校正信号;计算装置（2），用于计算校正信号以将磁带头返回到轨道的中心;锯齿 用于产生与磁带速度（v）相关的信号的发生器（2,4）以及用于响应锯齿和校正信号移动磁带头的磁头驱动机构（9）。
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公开(公告)号：USD540218S1
公开(公告)日：2007-04-10
申请号：US29210205
申请日：2004-07-29
Applicant: Toru Sekiguchi
Designer： Toru Sekiguchi
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