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公开(公告)号:US5456746A
公开(公告)日:1995-10-10
申请号:US153519
申请日:1993-11-16
申请人: Toshio Kokubun , Hiroshi Ohnuki , Toyokazu Shimizu
发明人: Toshio Kokubun , Hiroshi Ohnuki , Toyokazu Shimizu
IPC分类号: C08K5/10 , A61K9/48 , C08L89/00 , C08L89/04 , C09D189/00
CPC分类号: A61K9/4825
摘要: A hard film composition for capsules comprising a gelatin, from 3 to 10% by weight of an ester of a fatty acid and glycerol or polyglycerol. The capsules formed by the composition of the invention are not embrittled when the moisture in the capsule film is reduced by charging therein a hygroscopic drug, Consequently, cracking and chipping of the capsule are reduced and leakage from the capsule caused by such damage is also reduced.
摘要翻译: 用于胶囊的硬膜组合物,其包含明胶,3至10重量%的脂肪酸和甘油或聚甘油的酯。 当本发明的组合物形成的胶囊通过在其中吸收吸湿药物而减少胶囊膜中的水分而不会变脆。因此,胶囊的破裂和碎裂减少,并且由这种损伤引起的胶囊泄漏也降低 。