专利检索 ap:("TrueBinding, Inc.") AND inv:"Yan He" 第 1 页

1.

发明公开
ANTI-GAL3 ANTIBODY FORMULATIONS AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20240158512A1

公开(公告)日：2024-05-16

申请号：US18492607

申请日：2023-10-23

申请人： TrueBinding, Inc.

发明人： Dongxu Sun , Yan He , Fan Chen , Apurva Chandalia , Ksenya Shchors

IPC分类号： C07K16/28 , A61K47/02 , A61K47/20 , A61K47/22 , A61K47/26 , A61P25/28

CPC分类号： C07K16/2851 , A61K47/02 , A61K47/20 , A61K47/22 , A61K47/26 , A61P25/28

摘要： Disclosed herein are pharmaceutical antibody formulations for the treatment of a disease. The pharmaceutical antibody formulations comprise an antibody that binds to Galectin-3 (Gal3) and one or more excipients, diluents, salts, buffers, and the like. Also disclosed herein are sterile vials comprising these pharmaceutical antibody formulations, optionally in a concentrated form that is diluted prior to administration. The pharmaceutical antibody formulations are used to treat a disease such as a neurodegenerative disease, proteopathy, and/or inflammation associated with the aforementioned diseases.