公开(公告)号：US20240051976A1

公开(公告)日：2024-02-15

申请号：US18269916

申请日：2021-12-23

Applicant: Turun Yliopisto

Inventor： Anu AIRAKSINEN ,  sofia OTARU ,  Andreas PAULUS ,  Mirrka SARPARANTA

IPC: C07F5/02 ,  C07B59/00

CPC classification number: C07F5/027 ,  C07B59/004 ,  C07B2200/05

Abstract: A tracer compound, or a pharmaceutically acceptable salt or solvate thereof is disclosed, the tracer compound having a structure comprising of a tetrazine moiety, a zwitterion moiety and a linker moiety, the linker moiety linking together the tetrazine moiety and the zwitterion moiety, and the linker moiety being comprised of specific parts S1-Y—S2 disclosed herein. Furthermore, an adduct of the tracer compound and a trans-cyclooctene (TCO)-derivatized targeting moiety, and a method for manufacturing the tracer compound and the adduct are disclosed.