公开(公告)号：US20230066280A1

公开(公告)日：2023-03-02

申请号：US17793221

申请日：2021-01-18

Applicant: UCL BUSINESS LTD

Inventor： Melissa RAYNER ,  James PHILLIPS ,  Jess HEALY ,  Duncan CRAIG ,  Gareth WILLIAMS ,  Ana Rita Marques Pereira TRINDADE ,  Karolina DZIEMIDOWICZ ,  Victoria ROBERTON ,  Holly GREGORY ,  Desponia ELEFTHERIADOU

IPC: A61L27/36 ,  A61L27/18 ,  A61L27/54 ,  A61L27/58 ,  A61K31/192

Abstract: The invention relates to a nanofibrous material comprising a drug for treating a peripheral nerve injury by delivering the drug locally to a damaged or injured nerve. The drug may be such a Non Steroidal Anti Inflammatory Drug or a PPAR agonist. In particular, the invention relates to a drug eluting nerve wrap or bandage that can be wrapped around an injured peripheral nerve. The invention also relates to a nanofibrous drug delivery system or device for delivering a drug locally to a peripheral nerve, a treatment for a peripheral nerve injury comprising contacting a damaged nerve with the drug eluting nanofibrous material or drug delivery system, kits and methods for making the nanofibrous materials, and uses of the nanofibrous materials.