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公开(公告)号：US20220301158A1
公开(公告)日：2022-09-22
申请号：US17631258
申请日：2020-06-03
申请人： UNIVERSITE DE BORDEAUX , CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - (INSERM)
发明人： Gael DOURNES , Ilyes BENLALA , François LAURENT , Patrick BERGER
摘要： A Method for generating a biomarker includes acquiring an image using an MRI system; processing the MRI image to generate a three-dimensional image of the lung; generating a first function corresponding to the distribution of the different signal intensity values; automatically calculating a filtering threshold of the first function from a second signal intensity value distribution function; segmenting a lung volume comprising: a main volume; a filtered volume of a volume of voxels quantified by the first function and filtered by at least the calculated filtering threshold, normalizing the values of the three-dimensional image of the lung volume; generating a biomarker indicating a normalized segmented volume ratio.
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公开(公告)号：US20190172202A1
公开(公告)日：2019-06-06
申请号：US16304574
申请日：2017-05-29
申请人： UNIVERSITE DE BORDEAUX , L'INSTITUT POLYTECHNIQUE DE BORDEAUX , CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
摘要： An MRI method is disclosed for the geometrical characterisation of pulmonary airways on the basis of a first tridimensional image of at least one bronchus of a bronchial tree and includes: acquiring a first MRI image, an MRI sequence being synchronised with a respiratory frequency; filtering the first image; segmenting a portion of the filtered image including the contours of the bronchial tree and its inner volumetric portion; estimating at least one plane of cut of a bronchus; generating at least one image slice of a bronchus; estimating, for each image slice, an area contained within the bronchial wall and/or a bronchial wall thickness.
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