公开(公告)号：US12180165B2

公开(公告)日：2024-12-31

申请号：US17472371

申请日：2021-09-10

Applicant: University of Kansas

Inventor： Sunil A. David ,  Mallesh Beesu ,  Giuseppe Caruso ,  Alex Salyer

IPC: C07D215/38 ,  A61K45/06 ,  A61P37/02 ,  A61K39/39

Abstract: The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein.

公开(公告)号：US20180258045A1

公开(公告)日：2018-09-13

申请号：US15754193

申请日：2016-08-19

Applicant: UNIVERSITY OF KANSAS

Inventor： Sunil A. David ,  Mallesh Beesu ,  Giuseppe Caruso ,  Alex Salyer

IPC: C07D215/38 ,  A61P37/02

CPC classification number: C07D215/38 ,  A61K39/39 ,  A61K45/06 ,  A61P37/02

Abstract: The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein.

公开(公告)号：US20220002251A1

公开(公告)日：2022-01-06

申请号：US17472371

申请日：2021-09-10

Applicant: University of Kansas

Inventor： Sunil A. David ,  Mallesh Beesu ,  Giuseppe Caruso ,  Alex Salyer

IPC: C07D215/38 ,  A61K45/06 ,  A61P37/02

Abstract: The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein.

公开(公告)号：US11130736B2

公开(公告)日：2021-09-28

申请号：US15754193

申请日：2016-08-19

Applicant: UNIVERSITY OF KANSAS

Inventor： Sunil A. David ,  Mallesh Beesu ,  Giuseppe Caruso ,  Alex Salyer

IPC: C07D215/38 ,  A61P37/02 ,  A61K45/06 ,  A61K39/39

Abstract: The disclosure provides human toll-like receptor modulators of general Formula (II), wherein R1, R2, R3, R4, R5, R6, R7, R8 are defined herein.