公开(公告)号：US11208379B2

公开(公告)日：2021-12-28

申请号：US16672481

申请日：2019-11-03

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Craig A. Grapperhaus ,  Robert M. Buchanan ,  Nicholas S. Vishnosky ,  Jason O. E. Young ,  Paula J. Bates ,  Sarah A. Andres ,  Caleb Aaron Calvary

IPC: C07C335/40 ,  A61P35/00 ,  C07D265/30

Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I) or (Ia)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein.

公开(公告)号：US20200062703A1

公开(公告)日：2020-02-27

申请号：US16672481

申请日：2019-11-03

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Craig A. Grapperhaus ,  Robert M. Buchanan ,  Nicholas S. Vishnosky ,  Jason O. E. Young ,  Paula J. Bates ,  Sarah A. Andres ,  Caleb Aaron Calvary

IPC: C07C335/40 ,  C07D265/30 ,  A61P35/00

Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I) or (Ia)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein.