公开(公告)号：US11142835B2

公开(公告)日：2021-10-12

申请号：US16214088

申请日：2018-12-09

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Craig A. Grapperhaus ,  Robert M. Buchanan ,  Andrew Z. Haddad ,  Caleb Aaron Calvary

IPC: C25B11/04 ,  C07C337/06 ,  C07F3/06 ,  C07F1/08 ,  C07F15/04 ,  C25B1/04 ,  C07F15/06 ,  C07D323/00 ,  C07F3/00 ,  C07F1/00 ,  C25B11/075 ,  C25B11/095

Abstract: In some embodiments, this application relates to inventive compounds (e.g., Formula (I), Formula (II), thiosemicarbazones and/or thiosemicarbazones and their metal (e.g., zinc, cobalt, nickel, or copper) complexes, and extended structures thereof), methods for preparation of the inventive compounds, compositions comprising the inventive compounds (e.g., anode, cathodes, catalysts (e.g., electrocatalysts), glassy carbon electrodes, carbon paste electrodes, covalently modified carbon (e.g., modified graphene)), electrochemical cells comprising compositions that comprise one or more inventive compounds, fuel cells comprising compositions that comprise one or more inventive compounds, uses of one or more inventive compounds to produce H2 (e.g., via an electrochemical cell), and uses of one or more inventive compounds to create energy from H2 (e.g., via a fuel cell). Additional embodiments of the invention are also discussed herein.

公开(公告)号：US11078148B2

公开(公告)日：2021-08-03

申请号：US16803027

申请日：2020-02-27

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Steve P. Cronin ,  Craig A. Grapperhaus ,  Robert M. Buchanan ,  Jacob M. Strain ,  Joshua M. Spurgeon

IPC: C07C51/41 ,  B01J31/18 ,  C25B3/04 ,  C25B11/04 ,  C25B11/12 ,  C07C53/06 ,  C25B3/25 ,  C25B11/043 ,  C25B11/057

Abstract: Some embodiments of the invention include methods of using a compound (e.g., Formula (I)) for the reduction of carbon dioxide to formate by contacting the carbon dioxide with a composition comprising a compound. In certain embodiments, the source of the carbon dioxide is air or is flue gas. Additional embodiments of the invention are also discussed herein.

公开(公告)号：US11208379B2

公开(公告)日：2021-12-28

申请号：US16672481

申请日：2019-11-03

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Craig A. Grapperhaus ,  Robert M. Buchanan ,  Nicholas S. Vishnosky ,  Jason O. E. Young ,  Paula J. Bates ,  Sarah A. Andres ,  Caleb Aaron Calvary

IPC: C07C335/40 ,  A61P35/00 ,  C07D265/30

Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I) or (Ia)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein.

公开(公告)号：US20200062703A1

公开(公告)日：2020-02-27

申请号：US16672481

申请日：2019-11-03

Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.

Inventor： Craig A. Grapperhaus ,  Robert M. Buchanan ,  Nicholas S. Vishnosky ,  Jason O. E. Young ,  Paula J. Bates ,  Sarah A. Andres ,  Caleb Aaron Calvary

IPC: C07C335/40 ,  C07D265/30 ,  A61P35/00

Abstract: Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I) or (Ia)). Other embodiments include compositions (e.g., pharmaceutical compositions) comprising the inventive compound. Still other embodiments of the invention include compositions (e.g., pharmaceutical compositions) for treating, for example, certain diseases using the inventive compounds. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as cancer). Further embodiments include methods for making the inventive compounds. Additional embodiments of the invention are also discussed herein.