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1.发明申请公开(公告)号：US20180222900A1
公开(公告)日：2018-08-09
申请号：US15749652
申请日：2016-08-04
Applicant: UNIVERSITY OF SOUTH AUSTRALIA
Inventor： Shudong WANG , Solomon Tadesse ZELEKE , Mingfeng YU
IPC: C07D417/14 , A61P35/02
Abstract: A novel class of inhibitors of protein kinases that are useful in the treatment of cell proliferative diseases and conditions, and especially those characterised by over-expression of CDK4, CDK6 and/or cyclin D, including certain cancers of lung, breast, brain, central nervous system, colorectal cancer and leukaemias. The inhibitors have the general structure I:
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2.发明申请公开(公告)号：US20200283431A1
公开(公告)日：2020-09-10
申请号：US16599354
申请日：2019-10-11
Applicant: UNIVERSITY OF SOUTH AUSTRALIA
Inventor： Shudong WANG , Solomon Tadesse ZELEKE , Mingfeng YU
IPC: C07D417/14 , A61P35/02
Abstract: A novel class of inhibitors of protein kinases that are useful in the treatment of cell proliferative diseases and conditions, and especially those characterised by over-expression of CDK4, CDK6 and/or cyclin D, including certain cancers of lung, breast, brain central nervous system, colorectal cancer and leukaemias. The inhibitors have the general structure I:
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