公开(公告)号：US11896645B2

公开(公告)日：2024-02-13

申请号：US17177614

申请日：2021-02-17

申请人： UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG

发明人： Stefan Franz Thomas Weiss ,  Boitelo Theresiah Letsolo ,  Kerrilyn Naidoo ,  Tyrone Chad Otgaar

IPC分类号： A61K38/17 ,  C12N15/113 ,  C07K14/705 ,  A61P17/06 ,  A61P21/00 ,  A61P9/10 ,  A61P39/00 ,  A61P3/10 ,  A61P35/04 ,  A61P19/10 ,  A61K39/395 ,  C07K16/28

CPC分类号： A61K38/177 ,  A61K39/395 ,  A61P3/10 ,  A61P9/10 ,  A61P17/06 ,  A61P19/10 ,  A61P21/00 ,  A61P35/04 ,  A61P39/00 ,  C07K14/70546 ,  C07K16/28 ,  C12N15/113 ,  C12N2310/14

摘要： The invention relates to compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions, particularly wherein said telomere related diseases and/or telomere related medical conditions are cancer and cellular ageing. Particularly, herein is disclosed 37 kDa/67 kDa laminin receptor precursor/high affinity laminin receptor (LRP/LR) and/or a fragment thereof for use in the treatment and/or prevention of cellular ageing.

公开(公告)号：US20210169974A1

公开(公告)日：2021-06-10

申请号：US17177614

申请日：2021-02-17

申请人： UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG

发明人： Stefan Franz Thomas Weiss ,  Boitelo Theresiah Letsolo ,  Kerrilyn Naidoo ,  Tyrone Chad Otgaar

IPC分类号： A61K38/17 ,  C12N15/113 ,  A61P17/06 ,  A61P21/00 ,  A61P9/10 ,  A61P39/00 ,  A61P3/10 ,  A61P35/04 ,  A61P19/10 ,  A61K39/395 ,  C07K14/705 ,  C07K16/28

摘要： The invention relates to compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions, particularly wherein said telomere related diseases and/or telomere related medical conditions are cancer and cellular ageing. Particularly, herein is disclosed 37 kDa/67 kDa laminin receptor precursor/high affinity laminin receptor (LRP/LR) and/or a fragment thereof for use in the treatment and/or prevention of cellular ageing.

公开(公告)号：US20180325997A1

公开(公告)日：2018-11-15

申请号：US15773453

申请日：2016-11-07

申请人： UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG

发明人： Stefan Franz Thomas Weiss ,  Boitelo Theresiah Letsolo ,  Kerrilyn Naidoo ,  Tyrone Chad Otgaar

IPC分类号： A61K38/17 ,  C07K14/705 ,  A61K39/395 ,  A61P17/06 ,  A61P19/10 ,  A61P21/00 ,  A61P3/10 ,  A61P35/04 ,  A61P39/00 ,  A61P9/10 ,  C07K16/28 ,  C12N15/113

CPC分类号： A61K38/177 ,  A61K39/395 ,  A61P3/10 ,  A61P9/10 ,  A61P17/06 ,  A61P19/10 ,  A61P21/00 ,  A61P35/04 ,  A61P39/00 ,  C07K14/70546 ,  C07K16/28 ,  C12N15/113 ,  C12N2310/14

摘要： The invention relates to compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions, particularly wherein said telomere related diseases and/or telomere related medical conditions are cancer and cellular ageing. Particularly, herein is disclosed 37 kDa/67 kDa laminin receptor precursor/high affinity laminin receptor (LRP/LR) and/or a fragment thereof for use in the treatment and/or prevention of cellular ageing.