CRYOPRESERVATION OF CELLS IN ABSENCE OF VITRIFICATION INDUCING AGENTS

    公开(公告)号:US20190059360A1

    公开(公告)日:2019-02-28

    申请号:US16018555

    申请日:2018-06-26

    Abstract: The present invention relates to a method for cryopreserving biological material. In particular, the method comprises storing the biological material at a cryopreserving temperature in a composition comprising polyvinyl alcohol (PVA), wherein the composition is substantially free of vitrification-inducing agents such as DMSO and glycerol. The invention also provides methods of inhibiting ice recrystallisation and of reducing cell damage during the warming or thawing of a cryopreserved composition comprising biological material. The invention also relates to processes for producing a biological material, and related kits.

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