公开(公告)号：US20210094949A1

公开(公告)日：2021-04-01

申请号：US16960541

申请日：2019-06-12

Applicant: UNIVERSITY OF WASHINGTON ,  THE UNIVERSITY OF MONTANA

Inventor： Nephi STELLA ,  Philippe DIAZ

IPC: C07D471/04

Abstract: This disclosure relates to compounds that target microtubules, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases. More particularly, this disclosure relates to modified carbazole compounds and pharmaceutical compositions thereof, methods of targeting microtubules with these compounds, and methods of treating diseases affected by microtubule disruption.

公开(公告)号：US20220380367A1

公开(公告)日：2022-12-01

申请号：US17813318

申请日：2022-07-18

Applicant: UNIVERSITY OF WASHINGTON ,  THE UNIVERSITY OF MONTANA

Inventor： Nephi STELLA ,  Philippe DIAZ

IPC: C07D471/04

Abstract: This disclosure relates to compounds that target microtubules, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases. More particularly, this disclosure relates to modified carbazole compounds and pharmaceutical compositions thereof, methods of targeting microtubules with these compounds, and methods of treating diseases affected by microtubule disruption.